Browse Pet Safety Reports
16,709 FDA adverse event reports for pets.
FDA Veterinary Adverse Event Database
Browse 16,709 adverse event reports collected by the FDA's Center for Veterinary Medicine. Each report includes the animal species, breed, drug or product involved, observed reactions, and outcome. Reports flagged as "serious" involve death, life-threatening conditions, or hospitalization. Use the filters to narrow results by species, outcome severity, or keyword. Note that a higher number of reports does not necessarily indicate a less safe product, widely prescribed drugs naturally accumulate more reports.
Pet Adverse Event Reports
Browse 16,709 FDA veterinary adverse event reports for Human.
| Date | Species | Breed | Drug | Reaction | Outcome |
|---|---|---|---|---|---|
| Dec 18, 2017 | Human | Unknown | Tulathromycin | Injection site lesion | Outcome Unknown |
| Dec 16, 2017 | Human | Unknown | Gamithromycin | Injection site swelling; Injection site pain | Ongoing |
| Dec 14, 2017 | Human | Unknown | Orbifloxacin Oral Suspension | Burning sensation of eye; Medication error | Ongoing |
| Dec 12, 2017 | Human | Unknown | Florfenicol; Terbinafine; Betamethasone | Numbness; Pain NOS; Reddening of the skin | Ongoing |
| Dec 12, 2017 | Human | Unknown | Doramectin | Injection site reaction NOS; Injection site swelling | Ongoing |
| Dec 11, 2017 | Human | Unknown | Dinoprost Tromethamine | Injection site reaction NOS; Injection site bleeding | Recovered/Normal |
| Dec 8, 2017 | Human | Unknown | Melarsomine Dihydrochloride | Bad taste | Outcome Unknown |
| Dec 8, 2017 | Human | Unknown | Cyclosporine | Tingling sensation; Localised numbness (see also application site SOC); Accid... | Recovered/Normal |
| Dec 8, 2017 | Human | Unknown | Melarsomine Dihydrochloride | Eye irritation | Recovered/Normal |
| Dec 6, 2017 | Human | Unknown | Selamectin | Burning sensation of eye; Accidental exposure | Recovered/Normal |
| Dec 6, 2017 | Human | Unknown | Tilmicosin | Tingling sensation; Numbness; Accidental exposure | Recovered/Normal |
| Dec 6, 2017 | Human | Unknown | Fluralaner Spot-On Solution | Application site skin change NOS | Ongoing |
| Dec 5, 2017 | Human | Unknown | Florfenicol; Terbinafine Hydrochlorid... | Eye irritation | Outcome Unknown |
| Dec 5, 2017 | Human | Unknown | Fluralaner Spot-On Solution | Application site skin change NOS; Difficulty of Use | Ongoing |
| Dec 4, 2017 | Human | Unknown | Fluralaner Spot-On Solution | Application site skin change NOS | Recovered/Normal |
| Dec 3, 2017 | Human | Unknown | Florfenicol/Flunixin Inj-Triac | Injection site pain | Outcome Unknown |
| Dec 2, 2017 | Human | Unknown | Amoxicillin Trihydrate;Clavulanate Po... | Hives (see also 'Skin'); Swelling around eye; Throat tightness; Pharyngeal oe... | Recovered/Normal |
| Dec 1, 2017 | Human | Unknown | Prednisolone; Miconazole; Polymyxin B | Ringing in the ear; Increased sensitivity to sound; Medication error | Ongoing |
| Dec 1, 2017 | Human | Unknown | Afoxolaner | Hives (see also 'Skin'); Anaphylaxis | Recovered/Normal |
| Dec 1, 2017 | Human | Unknown | Phytosphingosine Salicyloyl; Ketocona... | Application site irritation | Recovered/Normal |
| Dec 1, 2017 | Human | Unknown | Tilmicosin | Injection site swelling; Accidental exposure | Recovered/Normal |
| Nov 30, 2017 | Human | Unknown | Fluralaner Spot-On Solution | Application site skin change NOS | Recovered/Normal |
| Nov 30, 2017 | Human | Unknown | Sarolaner | Reddening of the skin; Local swelling (not application site); Itching; Skin w... | Outcome Unknown |
| Nov 28, 2017 | Human | Unknown | Clomipramine | Drowsiness - systemic disorder; Light headedness | Recovered/Normal |
| Nov 28, 2017 | Human | Unknown | Fluralaner Spot-On Solution | Application site skin change NOS | Outcome Unknown |
| Nov 25, 2017 | Human | Unknown | Praziquantel; Emodepside | Urticaria; Skin warmth; Eosinophilia; Pruritus; Stinging skin; Other abnormal... | Recovered/Normal |
| Nov 24, 2017 | Human | Unknown | Fluralaner Spot-On Solution | Application site skin change NOS; Vials, Leaking | Outcome Unknown |
| Nov 24, 2017 | Human | Unknown | Fluralaner Spot-On Solution | Application site skin change NOS; Vials, Leaking | Recovered/Normal |
| Nov 22, 2017 | Human | Unknown | Pentobarbital/Phenytoin Inj | Unresponsive to stimuli | Outcome Unknown |
| Nov 21, 2017 | Human | Unknown | Florfenicol; Terbinafine Hydrochlorid... | Periorbital oedema | Recovered/Normal |
| Nov 20, 2017 | Human | Unknown | Fluralaner Spot-On Solution | Application site skin change NOS | Recovered/Normal |
| Nov 19, 2017 | Human | Unknown | Fluralaner Spot-On Solution | Application site skin change NOS; Taste alteration; Vials, Leaking | Ongoing |
| Nov 18, 2017 | Human | Unknown | Imidacloprid; Moxidectin | Burning mouth sensation; Accidental exposure | Outcome Unknown |
| Nov 18, 2017 | Human | Unknown | Fluralaner Spot-On Solution | Application site skin change NOS | Ongoing |
| Nov 17, 2017 | Human | Unknown | Sarolaner | Eye itching; Itchy skin | Recovered/Normal |
| Nov 17, 2017 | Human | Unknown | Moxidectin | Injection site swelling; Accidental exposure | Outcome Unknown |
| Nov 16, 2017 | Human | Unknown | Imidacloprid; Moxidectin | Application site burning sensation; Accidental exposure | Recovered/Normal |
| Nov 16, 2017 | Human | Unknown | Fluralaner Spot-On Solution | Application site skin change NOS; Labels, Abnormal; Containers, Leaking; Disp... | Recovered/Normal |
| Nov 15, 2017 | Human | Unknown | Spinosad | Reddening of the skin; Burning sensation (skin); Accidental exposure | Recovered/Normal |
| Nov 15, 2017 | Human | Unknown | Cyclosporine | Eye redness; Eyelid oedema; Tear flow increased; Eye stinging; Eye inflamed; ... | Ongoing |
| Nov 15, 2017 | Human | Unknown | Phytosphingosine Salicyloyl; Chlorhex... | Application site dry skin; Application site burning sensation | Recovered/Normal |
| Nov 14, 2017 | Human | Unknown | Tulathromycin | Injection site reaction NOS | Outcome Unknown |
| Nov 13, 2017 | Human | Unknown | Selamectin | Pruritus; Tubes, Leaking; Accidental exposure | Outcome Unknown |
| Nov 13, 2017 | Human | Unknown | Tylosin Tartrate | Localised numbness (see also application site SOC) | Recovered/Normal |
| Nov 12, 2017 | Human | Unknown | Cyclosporine | Burning mouth sensation | Recovered/Normal |
| Nov 11, 2017 | Human | Unknown | Ivermectin 10 Mg/Ml Solution For Inje... | Loss of consciousness; Injection site haematoma; Injection site pain; Lameness | Outcome Unknown |
| Nov 10, 2017 | Human | Unknown | Tulathromycin | Injection site reaction NOS; Injection site pain; Injection site swelling | Outcome Unknown |
| Nov 10, 2017 | Human | Unknown | Fluralaner Spot-On Solution | Application site skin change NOS; Dispenser, Abnormal | Outcome Unknown |
| Nov 10, 2017 | Human | Unknown | Fluralaner Spot-On Solution | Application site skin change NOS; Dispenser, Abnormal; Difficulty of Use; Tub... | Outcome Unknown |
| Nov 10, 2017 | Human | Unknown | Cefovecin | Swelling NOS; Breathing difficulty; Hives (see also 'Skin') | Outcome Unknown |
Frequently Asked Questions
Contact your veterinarian immediately. If the reaction is severe, difficulty breathing, seizures, collapse, or severe swelling, seek emergency veterinary care right away. After your pet is stabilized, report the adverse event to the FDA through safetyreporting.hhs.gov or by calling 1-888-FDA-VETS (1-888-332-8387). Reporting helps the FDA identify safety issues that can lead to label changes or product recalls.
Dogs account for the majority of adverse event reports, followed by cats. This reflects both the larger pet population and wider range of medications for these species. Flea and tick products, pain medications (NSAIDs), and heartworm preventives are among the product categories with the highest report counts across all species.
Not necessarily. A drug used by millions of pets will have more reports in absolute numbers than a niche product, even if the actual rate of adverse events is lower. The FDA uses these reports as one of many tools to evaluate drug safety, looking for patterns and statistical signals rather than raw counts alone. Always consult your veterinarian before changing any medication.