Browse Pet Safety Reports

16,709 FDA adverse event reports for pets.

FDA Veterinary Adverse Event Database

Browse 16,709 adverse event reports collected by the FDA's Center for Veterinary Medicine. Each report includes the animal species, breed, drug or product involved, observed reactions, and outcome. Reports flagged as "serious" involve death, life-threatening conditions, or hospitalization. Use the filters to narrow results by species, outcome severity, or keyword. Note that a higher number of reports does not necessarily indicate a less safe product, widely prescribed drugs naturally accumulate more reports.

Pet Adverse Event Reports

Browse 16,709 FDA veterinary adverse event reports for Human.

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Date Species Breed Drug Reaction Outcome
Sep 28, 2018 Human Unknown Clomipramine Nausea; Diarrhoea; Increased sweating Outcome Unknown
Sep 27, 2018 Human Unknown Altrenogest Oily Solution Bad taste Ongoing
Sep 26, 2018 Human Unknown Phytosphingosine Salicyloyl; Chlorhex... Pruritus Ongoing
Sep 26, 2018 Human Unknown Ivermectin Lethargy (see also Central nervous system depression in 'Neurological'); Naus... Recovered/Normal
Sep 26, 2018 Human Unknown Phytosphingosine Salicyloyl; Chlorhex... Pruritus; Urticaria Ongoing
Sep 25, 2018 Human Unknown Mirtazapine Eye irritation; Headache; Accidental exposure Outcome Unknown
Sep 25, 2018 Human Unknown Copper Naphthenate Skin irritation Recovered/Normal
Sep 24, 2018 Human Unknown Fluralaner Spot-On Solution Application site skin change NOS; Dispenser, Abnormal; Difficulty of Use; Pat... Recovered/Normal
Sep 24, 2018 Human Unknown Cefovecin Eye pain; Accidental exposure; Eye irritation Outcome Unknown
Sep 21, 2018 Human Unknown Ceftiofur Hydrochloride Injection site reaction NOS; Numbness Recovered/Normal
Sep 21, 2018 Human Unknown Tilmicosin Trauma NOS; Bradycardia; Injection site lesion; Accidental exposure Outcome Unknown
Sep 21, 2018 Human Unknown Fluralaner Spot-On Solution Application site skin change NOS; Containers, Leaking Recovered/Normal
Sep 19, 2018 Human Unknown Neomycin Sulfate; Thiabendazole; Dexa... Eye irritation Recovered/Normal
Sep 17, 2018 Human Unknown Fluralaner Spot-On Solution Application site skin change NOS; Containers, Leaking; Dispenser, Abnormal Recovered/Normal
Sep 17, 2018 Human Unknown Fluralaner Spot-On Solution Application site skin change NOS Outcome Unknown
Sep 16, 2018 Human Unknown Imidacloprid Muscle spasm NOS Recovered/Normal
Sep 15, 2018 Human Unknown Fluralaner Chew Tablets Reddening of the skin; Tingling sensation Ongoing
Sep 15, 2018 Human Unknown Fluralaner Spot-On Solution Application site skin change NOS; Dispenser, Abnormal; Difficulty of Use Ongoing
Sep 13, 2018 Human Unknown Eprinomectin Nausea; Abnormal vision (see also impaired vision) Outcome Unknown
Sep 12, 2018 Human Unknown Nitenpyram Vomiting; Stomach upset; Nausea; Tongue disorder NOS; Dry mouth Ongoing
Sep 12, 2018 Human Unknown Melarsomine Dihydrochloride Burning sensation (skin); Accidental exposure Outcome Unknown
Sep 12, 2018 Human Unknown Fluralaner Spot-On Solution Application site skin change NOS; Difficulty of Use Ongoing
Sep 11, 2018 Human Unknown Fluralaner Spot-On Solution Application site skin change NOS; Dispenser, Abnormal; Difficulty of Use Ongoing
Sep 10, 2018 Human Unknown Fluralaner Spot-On Solution Dizziness; Unsteady gait; Headache Ongoing
Sep 10, 2018 Human Unknown Selamectin Mouth irritation; Oral mucosal blistering; Accidental exposure Outcome Unknown
Sep 10, 2018 Human Unknown Florfenicol; Terbinafine Hydrochlorid... Eye irritation; Eye redness; Eye pain Recovered/Normal
Sep 7, 2018 Human Unknown Nitenpyram Headache; Accidental exposure Recovered/Normal
Sep 6, 2018 Human Unknown Pregnyl/Gestyl 200/400 Injection site pain; Injection site swelling Recovered/Normal
Sep 5, 2018 Human Unknown Afoxolaner Urticaria Ongoing
Sep 5, 2018 Human Unknown Tilmicosin Injection site lesion; High blood pressure; Increased heart rate; Injection s... Recovered/Normal
Sep 4, 2018 Human Unknown Amoxicillin Trihydrate;Clavulanate Po... Increased sweating; Chest discomfort NOS; Fatigue; Nausea; Abdominal pain; Di... Ongoing
Sep 4, 2018 Human Unknown Tulathromycin Injection site reaction NOS Outcome Unknown
Sep 4, 2018 Human Unknown Fluralaner Spot-On Solution Diarrhoea Ongoing
Sep 4, 2018 Human Unknown Fluralaner Spot-On Solution Bad taste Ongoing
Sep 4, 2018 Human Unknown Nitenpyram Increased heart rate; Chest discomfort NOS; Accidental exposure Recovered/Normal
Sep 3, 2018 Human Unknown Fluralaner Spot-On Solution Application site skin change NOS Ongoing
Sep 3, 2018 Human Unknown Imidacloprid; Moxidectin Feeling anxious; Accidental exposure Outcome Unknown
Sep 3, 2018 Human Unknown Fluralaner Spot-On Solution Application site skin change NOS Ongoing
Sep 3, 2018 Human Unknown Selamectin Itchy rash; Skin lump; Hives (see also 'Skin'); Wheezing Outcome Unknown
Sep 2, 2018 Human Unknown Fluralaner Spot-On Solution Application site skin change NOS; Labels, Abnormal; Difficulty of Use Recovered/Normal
Aug 31, 2018 Human Unknown Fluralaner Spot-On Solution Application site skin change NOS; Dispenser, Abnormal; Tubes, Leaking Ongoing
Aug 30, 2018 Human Unknown Tylosin Injection site pain; Accidental exposure Ongoing
Aug 29, 2018 Human Unknown Fluralaner Spot-On Solution Application site skin change NOS Recovered/Normal
Aug 29, 2018 Human Unknown Fluralaner Chew Tablets Nerve pain NOS; Neurological signs NOS Recovered/Normal
Aug 28, 2018 Human Unknown Fluralaner Spot-On Solution Application site dry skin Recovered/Normal
Aug 28, 2018 Human Unknown Imidacloprid; Moxidectin Abdominal discomfort; Accidental exposure Recovered/Normal
Aug 28, 2018 Human Unknown Fluralaner Spot-On Solution Application site skin change NOS; Local swelling (not application site); Loca... Ongoing
Aug 27, 2018 Human Unknown Fluralaner Spot-On Solution Application site skin change NOS Outcome Unknown
Aug 27, 2018 Human Unknown Fluralaner Spot-On Solution Application site skin change NOS Recovered/Normal
Aug 27, 2018 Human Unknown Fluralaner Spot-On Solution Application site skin change NOS; Containers, Leaking; Dispenser, Abnormal Recovered/Normal

Frequently Asked Questions

Contact your veterinarian immediately. If the reaction is severe, difficulty breathing, seizures, collapse, or severe swelling, seek emergency veterinary care right away. After your pet is stabilized, report the adverse event to the FDA through safetyreporting.hhs.gov or by calling 1-888-FDA-VETS (1-888-332-8387). Reporting helps the FDA identify safety issues that can lead to label changes or product recalls.

Dogs account for the majority of adverse event reports, followed by cats. This reflects both the larger pet population and wider range of medications for these species. Flea and tick products, pain medications (NSAIDs), and heartworm preventives are among the product categories with the highest report counts across all species.

Not necessarily. A drug used by millions of pets will have more reports in absolute numbers than a niche product, even if the actual rate of adverse events is lower. The FDA uses these reports as one of many tools to evaluate drug safety, looking for patterns and statistical signals rather than raw counts alone. Always consult your veterinarian before changing any medication.