Browse Pet Safety Reports
1,334,160 FDA adverse event reports for pets.
FDA Veterinary Adverse Event Database
Browse 1,334,160 adverse event reports collected by the FDA's Center for Veterinary Medicine. Each report includes the animal species, breed, drug or product involved, observed reactions, and outcome. Reports flagged as "serious" involve death, life-threatening conditions, or hospitalization. Use the filters to narrow results by species, outcome severity, or keyword. Note that a higher number of reports does not necessarily indicate a less safe product, widely prescribed drugs naturally accumulate more reports.
Pet Adverse Event Reports
Browse 1,334,160 FDA veterinary adverse event reports.
| Date | Species | Breed | Drug | Reaction | Outcome |
|---|---|---|---|---|---|
| Mar 7, 2026 | Dog | Deutsche Dogge, Great Dane,... | Afoxolaner 150Mg / Moxidectin 720Mcg ... | Lack of efficacy (bacteria) - Borrelia; Lack of efficacy (bacteria) - Anaplasma | Ongoing |
| Mar 7, 2026 | Dog | Terrier - Bull - American P... | Pyrantel Pamoate;Sarolaner | Seizure NOS; Drooling; Pale mucous membrane; Collapse (see also Cardio-vascul... | Recovered/Normal |
| Mar 7, 2026 | Dog | Brittany | Pyrantel Pamoate;Sarolaner | Lack of efficacy (bacteria) - Anaplasma; Medication error NOS | Ongoing |
| Mar 7, 2026 | Dog | Retriever - Flat-coated | Ilunocitinib | Diarrhoea; Leukopenia NOS; Hepatic disorder NOS | Ongoing |
| Mar 7, 2026 | Dog | Terrier - West Highland White | Moxidectin | Lack of efficacy (endoparasite) - heartworm | Ongoing |
| Mar 7, 2026 | Dog | Crossbred Canine/dog, Deuts... | Fluralaner Powder For Inj Susp | Emesis (multiple); Nausea; Lethargy (see also Central nervous system depressi... | Ongoing |
| Mar 7, 2026 | Dog | Terrier - Jack Russell | Gentamicin Sulfate; Hydrocortisone Ac... | Loss of hearing | Outcome Unknown |
| Mar 7, 2026 | Dog | Siberian Husky | Pyrantel Pamoate;Sarolaner | Lack of efficacy (bacteria) - Borrelia; Lack of efficacy (ectoparasite) - tic... | Ongoing |
| Mar 7, 2026 | Dog | Hound (unspecified) | Pyrantel Pamoate;Sarolaner | Lack of efficacy (endoparasite) - heartworm | Ongoing |
| Mar 7, 2026 | Dog | Boxer (German Boxer) | Ivermectin; Pyrantel As Pamoate Salt | Lack of efficacy (endoparasite) - heartworm | Outcome Unknown |
| Mar 7, 2026 | Dog | Crossbred Canine/dog | Genta/Momet/Clotrim Ear Oint | Deafness | Recovered with Sequela |
| Mar 7, 2026 | Dog | Crossbred Canine/dog | Pyrantel Pamoate;Sarolaner | Lack of efficacy (bacteria) - Anaplasma; Medication error NOS | Ongoing |
| Mar 7, 2026 | Cat | Cat (unknown) | Nitenpyram | Lack of efficacy (ectoparasite) - flea | Outcome Unknown |
| Mar 7, 2026 | Dog | Terrier - West Highland White | Fluralaner Powder For Inj Susp | Lack of efficacy (ectoparasite) - flea | Ongoing |
| Mar 7, 2026 | Dog | Crossbred Canine/dog, Retri... | Fluralaner Powder For Inj Susp | Pawing; Localised itching; Rubbing; Emesis (multiple); External ear disorder ... | Ongoing |
| Mar 7, 2026 | Dog | Beagle | Spinosad; Milbemycin Oxime | Lack of efficacy (endoparasite) - heartworm | Outcome Unknown |
| Mar 7, 2026 | Dog | Terrier - Yorkshire | Fluralaner 13.64% 12-Week Chew | Abnormal movement NOS; Myoclonic jerk | Ongoing |
| Mar 7, 2026 | Dog | Terrier - Yorkshire | Pyrantel Pamoate;Sarolaner | Intentional misuse; Lack of efficacy (bacteria) - Ehrlichia; Lack of efficacy... | Ongoing |
| Mar 7, 2026 | Cat | Cat (unknown) | Nitenpyram | Lack of efficacy (ectoparasite) - flea | Outcome Unknown |
| Mar 7, 2026 | Dog | Dogue de Bordeaux | Bedinvetmab | Difficulty to rise; Discomfort NOS; Fever; Panting; Weakness; Knuckling; Leth... | Ongoing |
| Mar 7, 2026 | Dog | Crossbred Canine/dog | Gentamicin Sulfate, Usp; Mometasone F... | Loss of hearing | Recovered with Sequela |
| Mar 7, 2026 | Dog | Poodle - Standard | Capromorelin | Lack of efficacy - NOS | Outcome Unknown |
| Mar 7, 2026 | Dog | Chihuahua | Moxidectin | Vomiting | Recovered/Normal |
| Mar 7, 2026 | Dog | Rottweiler | Fluralaner Powder For Inj Susp | Injection site itching | Ongoing |
| Mar 7, 2026 | Dog | Shepherd Dog - German | Milbemycin Oxime; Praziquantel | Lack of efficacy (endoparasite) - heartworm; Drug dose omission | Outcome Unknown |
| Mar 7, 2026 | Dog | Shepherd Dog - German | Capromorelin | Pleural effusion; Respiratory distress; Lack of efficacy - NOS | Ongoing |
| Mar 7, 2026 | Dog | Chihuahua | Prednisolone; Miconazole; Polymyxin B | Loss of hearing; Deafness | Ongoing |
| Mar 7, 2026 | Dog | Crossbred Canine/dog | Ivermectin; Pyrantel | Lack of efficacy (endoparasite) - heartworm | Ongoing |
| Mar 7, 2026 | Dog | Bichon Frise | Chlorhexidine; Ophytrium | Application site inflammation | Recovered/Normal |
| Mar 7, 2026 | Dog | Terrier - Bull | Pyrantel Pamoate;Sarolaner | Tremor; Seizure NOS; Death | Died |
| Mar 7, 2026 | Dog | Chihuahua | Afoxolaner | Irritability; Restlessness | Recovered/Normal |
| Mar 7, 2026 | Cat | Domestic Longhair | Fluralaner Spot-On Solution | Lack of efficacy (ectoparasite) - flea | Ongoing |
| Mar 7, 2026 | Dog | Spaniel - Cocker American | Moxidectin | Drowsiness - systemic disorder; Seizure NOS; Nystagmus; Head tilt - neurologi... | Ongoing |
| Mar 7, 2026 | Dog | Chihuahua | Praziquantel; Febantel; Pyrantel Pamoate | Emesis (multiple) | Outcome Unknown |
| Mar 7, 2026 | Dog | Retriever - Labrador | Milbemycin/Lufenuron/Pzq Chew | Panting; Increased drinking; Inappropriate urination; Flatulence; Pacing; Sle... | Ongoing |
| Mar 7, 2026 | Dog | Poodle (unspecified) | Moxidectin | Facial swelling (see also Skin); Local erythema; Hypersensitivity reaction | Recovered/Normal |
| Mar 7, 2026 | Dog | Terrier (unspecified) | Afoxolaner 75Mg / Moxidectin 360Mcg /... | Lack of efficacy (bacteria) - Borrelia | Outcome Unknown |
| Mar 7, 2026 | Dog | Pointing Dog - German Short... | Enrofloxacin | Cough | Outcome Unknown |
| Mar 7, 2026 | Dog | Schnauzer - Miniature | Milbemycin Oxime; Praziquantel | Lack of efficacy (endoparasite) - roundworm NOS; Lack of efficacy (endoparasi... | Outcome Unknown |
| Mar 7, 2026 | Dog | Terrier - West Highland White | Fluralaner Powder For Inj Susp | Lack of efficacy (ectoparasite) - flea | Ongoing |
| Mar 7, 2026 | Dog | Terrier (unspecified) | Afoxolaner 75Mg / Moxidectin 360Mcg /... | Lack of efficacy (endoparasite) - heartworm | Outcome Unknown |
| Mar 7, 2026 | Dog | Hound (unspecified) | Fluralaner 13.64% 12-Week Chew | Lack of efficacy (ectoparasite) - flea | Ongoing |
| Mar 7, 2026 | Dog | Beagle | Ivermectin; Pyrantel | Lack of efficacy (endoparasite) - heartworm | Ongoing |
| Mar 7, 2026 | Dog | Spaniel (unspecified), Pood... | Pyrantel Pamoate;Sarolaner | Vomiting | Outcome Unknown |
| Mar 7, 2026 | Dog | Retriever - Labrador, Poodl... | Moxidectin | Head shake - behavioural disorder; Vomiting; Facial pruritus; Medication erro... | Recovered/Normal |
| Mar 7, 2026 | Dog | Bulldog - English | Afoxolaner 75Mg / Moxidectin 360Mcg /... | Lack of efficacy (bacteria) - Borrelia | Outcome Unknown |
| Mar 7, 2026 | Dog | Crossbred Canine/dog, Pit Bull | Fluralaner Powder For Inj Susp | Lethargy (see also Central nervous system depression in Neurological); Decrea... | Ongoing |
| Mar 7, 2026 | Dog | Corgi (unspecified), Dog (u... | Milbemycin Oxime; Praziquantel | Lack of efficacy (bacteria) - Borrelia | Outcome Unknown |
| Mar 7, 2026 | Dog | Beagle | Ivermectin; Pyrantel As Pamoate Salt | Lack of efficacy (endoparasite) - hookworm; Pancreatitis NOS | Ongoing |
| Mar 7, 2026 | Dog | Crossbred Canine/dog | Fluralaner 13.64% 12-Week Chew | Lack of efficacy (ectoparasite) - flea | Ongoing |
Frequently Asked Questions
Contact your veterinarian immediately. If the reaction is severe, difficulty breathing, seizures, collapse, or severe swelling, seek emergency veterinary care right away. After your pet is stabilized, report the adverse event to the FDA through safetyreporting.hhs.gov or by calling 1-888-FDA-VETS (1-888-332-8387). Reporting helps the FDA identify safety issues that can lead to label changes or product recalls.
Dogs account for the majority of adverse event reports, followed by cats. This reflects both the larger pet population and wider range of medications for these species. Flea and tick products, pain medications (NSAIDs), and heartworm preventives are among the product categories with the highest report counts across all species.
Not necessarily. A drug used by millions of pets will have more reports in absolute numbers than a niche product, even if the actual rate of adverse events is lower. The FDA uses these reports as one of many tools to evaluate drug safety, looking for patterns and statistical signals rather than raw counts alone. Always consult your veterinarian before changing any medication.