Browse Pet Safety Reports

31,013 FDA adverse event reports for pets.

FDA Veterinary Adverse Event Database

Browse 31,013 adverse event reports collected by the FDA's Center for Veterinary Medicine. Each report includes the animal species, breed, drug or product involved, observed reactions, and outcome. Reports flagged as "serious" involve death, life-threatening conditions, or hospitalization. Use the filters to narrow results by species, outcome severity, or keyword. Note that a higher number of reports does not necessarily indicate a less safe product, widely prescribed drugs naturally accumulate more reports.

Pet Adverse Event Reports

Browse 31,013 FDA veterinary adverse event reports for Cattle.

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Date Species Breed Drug Reaction Outcome
Dec 12, 2012 Cattle Cattle (unknown) Tulathromycin Lack of efficacy (bacteria) - NOS; Death Ongoing
Dec 12, 2012 Cattle Holstein-Friesian also know... Tulathromycin Residues in milk; Lack of efficacy (bacteria) - NOS Recovered/Normal
Dec 12, 2012 Cattle Cattle (unknown) Eprinomectin 0.5% Pour-On Fungal skin infection NOS; Hair loss NOS; Lack of efficacy (ectoparasite) - lice Outcome Unknown
Dec 12, 2012 Cattle Cattle (other) Tulathromycin Lack of efficacy (bacteria) - NOS; Death Died
Dec 12, 2012 Cattle Holstein-Friesian also know... Florfenicol External ear disorder NOS; Death Died
Dec 12, 2012 Cattle Holstein-Friesian also know... Tildipirosin Fever; Diarrhoea; DEATH-TREATMENT FAILURE; Lack of efficacy (bacteria) - NOS;... Died
Dec 11, 2012 Cattle Aberdeen Angus Amprolium Rectal bleeding; Haematochezia -
Dec 11, 2012 Cattle Aberdeen Angus Doramectin Pruritus Recovered/Normal
Dec 11, 2012 Cattle Holstein-Friesian also know... Florfenicol Fever; Death; PR-LUNG(S), LESION(S) Died
Dec 11, 2012 Cattle Holstein-Friesian also know... Estradiol, Trenbolone Acetate Increased sexual interest; Death; DEATH-SLAUGHTERED Died
Dec 11, 2012 Cattle Holstein-Friesian also know... Tildipirosin Depression; Fever; DEATH-TREATMENT FAILURE; PR-LUNG(S), LESION(S); Lack of ef... Died
Dec 10, 2012 Cattle Aberdeen Angus Doramectin Lack of efficacy - NOS Outcome Unknown
Dec 10, 2012 Cattle Cattle (unknown) Monensin Sodium Diarrhoea; Death; Decreased appetite; Not eating Died; Outcome Unknown
Dec 10, 2012 Cattle Cattle (other) Tulathromycin Lack of efficacy (bacteria) - NOS; Ruminal bloat; Death Died; Outcome Unknown
Dec 10, 2012 Cattle Cattle (other) Ceftiofur Crystalline Free Acid Increased mortality rate; Lack of efficacy (bacteria) - NOS Died
Dec 10, 2012 Cattle Holstein-Friesian also know... Monensin Sodium Ketosis Outcome Unknown
Dec 7, 2012 Cattle Holstein-Friesian also know... Ceftiofur Sodium No sign Euthanized
Dec 6, 2012 Cattle Cattle (other) Progesterone INEFFECTIVE, ESTRUS SYNCHRONIZ Outcome Unknown
Dec 6, 2012 Cattle Cattle (unknown) Moxidectin Lack of efficacy (ectoparasite) - lice -
Dec 6, 2012 Cattle Holstein-Friesian also know... Eprinomectin Digestive tract haemorrhage NOS; Death; PR-INTEST, LESION(S); Collapse (see a... Died
Dec 5, 2012 Cattle Cattle (other) Doramectin INEFFECTIVE, WORMS NOS Outcome Unknown
Dec 5, 2012 Cattle Crossbred Bovine/Cattle Monensin Sodium Not eating Recovered/Normal
Dec 5, 2012 Cattle Holstein-Friesian also know... Tildipirosin Fever; Depression; DEATH-TREATMENT FAILURE; Lack of efficacy (bacteria) - NOS... Died
Dec 4, 2012 Cattle Cattle (unknown) Tildipirosin DEATH-TREATMENT FAILURE; Lack of efficacy (bacteria) - NOS Died
Dec 4, 2012 Cattle Cattle (other) Ceftiofur Crystalline Free Acid Lack of efficacy (bacteria) - NOS; Abnormal necropsy finding; Pulmonary conge... Died; Outcome Unknown
Dec 4, 2012 Cattle Cattle (unknown) Florfenicol, Flunixin DEATH-TREATMENT FAILURE; Lack of efficacy (bacteria) - NOS Died
Dec 4, 2012 Cattle Cattle (other) Tulathromycin Increased mortality rate; Lack of efficacy (bacteria) - NOS Recovered/Normal; Died
Dec 4, 2012 Cattle Holstein-Friesian also know... Florfenicol, Flunixin Death; Septicaemia; PR-LIVER, LESION(S); PR-LUNG(S), LESION(S); PR-LYMPH NODE... Died
Dec 4, 2012 Cattle Aberdeen Angus Tulathromycin Injection site abscess Recovered/Normal
Dec 4, 2012 Cattle Brangus Fenbendazole Lack of efficacy (protozoa) - Coccidia; Lack of efficacy (endoparasite) - tap... -
Dec 4, 2012 Cattle Holstein-Friesian also know... Tildipirosin Fever; DEATH-TREATMENT FAILURE; PR-LUNG(S), LESION(S); Lack of efficacy (bact... Died
Dec 4, 2012 Cattle Holstein-Friesian also know... Florfenicol Death; PR-LUNG(S), LESION(S) Died
Dec 4, 2012 Cattle Holstein-Friesian also know... Flunixin Meglumine Death; PR-LUNG(S), LESION(S) Died
Dec 3, 2012 Cattle Holstein-Friesian also know... Monensin Sodium Diarrhoea; Decreased appetite; Melaena Recovered with Sequela
Dec 3, 2012 Cattle Cattle (other) Cephapirin Sodium Residues in milk Outcome Unknown
Dec 3, 2012 Cattle Brangus Tulathromycin Lack of efficacy (bacteria) - NOS; Death Ongoing; Died
Dec 3, 2012 Cattle Cattle (other) Dinoprost Tromethamine Lack of efficacy - NOS; INEFFECTIVE, ABORTION Outcome Unknown
Dec 3, 2012 Cattle Holstein-Friesian also know... Monensin Sodium INEFFECTIVE, PRODUCTION (MILK) Outcome Unknown
Dec 3, 2012 Cattle Cattle (unknown) Ivermectin INEFFECTIVE, LICE BITING -
Dec 3, 2012 Cattle Crossbred Bovine/Cattle Zilpaterol INEFFECTIVE, PRODUCTION (MEAT); Anorexia -
Dec 2, 2012 Cattle Crossbred Bovine/Cattle Ivermectin INEFFECTIVE, GRUBS -
Dec 1, 2012 Cattle Cattle (unknown) Monensin Sodium Not eating Recovered with Sequela
Dec 1, 2012 Cattle Holstein-Friesian also know... Monensin Sodium Recumbency; Death; Lethargy (see also Central nervous system depression in 'N... Recovered/Normal; Died; Outcome Unknown
Dec 1, 2012 Cattle Holstein-Friesian also know... Eprinomectin Lack of efficacy (ectoparasite) - mite NOS; DEATH-SLAUGHTERED -
Dec 1, 2012 Cattle Holstein-Friesian also know... Monensin Sodium Milk production decrease Recovered/Normal
Dec 1, 2012 Cattle Crossbred Bovine/Cattle Tildipirosin DEATH-TREATMENT FAILURE; Lack of efficacy (bacteria) - NOS Died
Dec 1, 2012 Cattle Crossbred Bovine/Cattle Florfenicol Lack of efficacy (bacteria) - NOS; Death Died
Dec 1, 2012 Cattle Crossbred Bovine/Cattle Tildipirosin Lack of efficacy (bacteria) - NOS; DEATH-TREATMENT FAILURE Died
Dec 1, 2012 Cattle Crossbred Bovine/Cattle Tildipirosin DEATH-TREATMENT FAILURE; Lack of efficacy (bacteria) - NOS Died
Dec 1, 2012 Cattle Holstein-Friesian also know... Dinoprost Tromethamine Myositis; DEATH-SLAUGHTERED Recovered/Normal; Euthanized

Frequently Asked Questions

Contact your veterinarian immediately. If the reaction is severe, difficulty breathing, seizures, collapse, or severe swelling, seek emergency veterinary care right away. After your pet is stabilized, report the adverse event to the FDA through safetyreporting.hhs.gov or by calling 1-888-FDA-VETS (1-888-332-8387). Reporting helps the FDA identify safety issues that can lead to label changes or product recalls.

Dogs account for the majority of adverse event reports, followed by cats. This reflects both the larger pet population and wider range of medications for these species. Flea and tick products, pain medications (NSAIDs), and heartworm preventives are among the product categories with the highest report counts across all species.

Not necessarily. A drug used by millions of pets will have more reports in absolute numbers than a niche product, even if the actual rate of adverse events is lower. The FDA uses these reports as one of many tools to evaluate drug safety, looking for patterns and statistical signals rather than raw counts alone. Always consult your veterinarian before changing any medication.