Browse Pet Safety Reports
1,068 FDA adverse event reports for pets.
FDA Veterinary Adverse Event Database
Browse 1,068 adverse event reports collected by the FDA's Center for Veterinary Medicine. Each report includes the animal species, breed, drug or product involved, observed reactions, and outcome. Reports flagged as "serious" involve death, life-threatening conditions, or hospitalization. Use the filters to narrow results by species, outcome severity, or keyword. Note that a higher number of reports does not necessarily indicate a less safe product — widely prescribed drugs naturally accumulate more reports.
Pet Adverse Event Reports
Browse 1,068 FDA veterinary adverse event reports for Sheep.
| Date | Species | Breed | Drug | Reaction | Outcome |
|---|---|---|---|---|---|
| Aug 15, 1988 | Sheep | Lincoln | Ivermectin | INEFFECTIVE, WORMS NOS | — |
| Aug 10, 1988 | Sheep | Sheep (unknown) | Ivermectin | Lack of efficacy (ectoparasite) - lice | — |
| Aug 10, 1988 | Sheep | Sheep (other) | Ivermectin | Circling - neurological disorder (see also 'Behavioural disorders'); Paresis;... | — |
| Aug 10, 1988 | Sheep | Crossbred Ovine/sheep | Ivermectin | Diarrhoea; PR-INTEST, LESION(S) | — |
| Aug 8, 1988 | Sheep | Sheep (unknown) | Arsanilic Acid | Death | Died |
| Aug 2, 1988 | Sheep | Sheep (other) | Ivermectin | Death; PR-KIDNEY(S), LESION(S); PR-LUNG(S), LESION(S); PR-STOMACH, LESION(S) | Died |
| Aug 2, 1988 | Sheep | Sheep (other) | Ivermectin | Death; PR-KIDNEY(S), LESION(S); PR-LUNG(S), LESION(S) | Died |
| Jul 14, 1988 | Sheep | Crossbred Ovine/sheep | Ivermectin | INEFFECTIVE, WORMS NOS | Died |
| Jul 14, 1988 | Sheep | Sheep (other) | Ivermectin | INEFFECTIVE, WORMS NOS | Died |
| Jul 11, 1988 | Sheep | Sheep (other) | Ivermectin | Infertility NOS | — |
| Jul 11, 1988 | Sheep | Sheep (other) | Ivermectin | INEFFECTIVE, STRONGYLES | Died |
| Jul 11, 1988 | Sheep | Crossbred Ovine/sheep | Ivermectin | INEFFECTIVE, WORMS NOS | Died |
| Jun 29, 1988 | Sheep | Suffolk sheep | Ivermectin | Death; Recumbency; Distension of abdomen; CULTURE/TITER DATA ABNORMAL; PR-LUN... | Died |
| Jun 24, 1988 | Sheep | Sheep (other) | Ivermectin | Loss of condition; INEFFECTIVE, WORMS NOS; Death | Died |
| Jun 24, 1988 | Sheep | Crossbred Ovine/sheep | Lincomycin Hydrochloride | Death | Died |
| Jun 24, 1988 | Sheep | Sheep (unknown) | Ivermectin | INEFFECTIVE, STRONGYLES | — |
| Jun 20, 1988 | Sheep | Crossbred Ovine/sheep | Ivermectin | INEFFECTIVE, STRONGYLES | — |
| Jun 16, 1988 | Sheep | Sheep (other) | Ivermectin | Lack of efficacy - NOS | — |
| Jun 16, 1988 | Sheep | Sheep (other) | Ivermectin | Hair modification NOS | — |
| Jun 8, 1988 | Sheep | Sheep (other) | Ivermectin | INEFFECTIVE, STRONGYLOIDS | — |
| Jun 2, 1988 | Sheep | Crossbred Ovine/sheep | Monensin | Death | Died |
| Apr 25, 1988 | Sheep | Sheep (unknown) | Ivermectin | Placental abnormality; Vulvitis | — |
| Mar 31, 1988 | Sheep | Crossbred Ovine/sheep | Amprolium, Ethopabate | Ataxia; Death; Anorexia; Malaise | Died |
| Feb 9, 1988 | Sheep | Sheep (unknown) | Dihydrostreptomycin, Penicillin G Pro... | Recumbency; Death | Died |
| Dec 10, 1987 | Sheep | Mixed (Sheep) | Monensin | Death; Weakness; Malaise; Respiratory tract disorder NOS | Died |
| Nov 5, 1987 | Sheep | Crossbred Ovine/sheep | Zeranol | Rectal prolapse; Vaginal prolapse | Died |
| Nov 3, 1987 | Sheep | Sheep (other) | Thiabendazole | Diarrhoea; Death | Died |
| Oct 12, 1987 | Sheep | Crossbred Ovine/sheep | Monensin | Death; PR-HEART, LESION(S); PR-LUNG(S), LESION(S) | Died |
| Aug 25, 1987 | Sheep | Sheep (unknown) | Levamisole Hydrochloride | Death | Died |
| Aug 13, 1987 | Sheep | Sheep (unknown) | Monensin | Diarrhoea; Muscle stiffness; Death; Depression; Hind limb paresis | Died |
| Jul 7, 1987 | Sheep | Suffolk sheep | Monensin | Convulsion; Ataxia; Death; Confusion | Died |
| Jul 1, 1987 | Sheep | Sheep (other) | Fenbendazole | Death; PR-LIVER, LESION(S); PR-LUNG(S), LESION(S); PR-TRACHEA, LESION(S) | Died |
| Jun 24, 1987 | Sheep | Suffolk sheep | Monensin | UNPALATABLE | — |
| Apr 10, 1987 | Sheep | Sheep (unknown) | Levamisole Hydrochloride | Hypersalivation; Death | Died |
| Mar 31, 1987 | Sheep | Sheep (other) | Ivermectin | Head pressing; Central nervous system disorder NOS; Death | Died |
| Feb 26, 1987 | Sheep | Sheep (other) | Ivermectin | Diarrhoea; Death; PR-KIDNEY(S), LESION(S); PR-LIVER, LESION(S); PR-LYMPH NODE... | Died |
| Jan 16, 1987 | Sheep | Sheep (unknown) | Ivermectin | Birth defect | — |
| Jan 14, 1987 | Sheep | Sheep (unknown) | Dihydrostreptomycin, Penicillin G Pro... | Anaphylaxis; Death | Died |
| — | Sheep | Sheep (unknown) | Pregnyl/Gestyl 200/400 | Medication error; Incorrect storage of drug; Hyperextension; INEFFECTIVE, EST... | Outcome Unknown |
| — | Sheep | Sheep (unknown) | Isoflurane | Product problem; Decreased packed cell volume (PCV); Decreased haemoglobin; H... | Outcome Unknown |
| — | Sheep | Sheep (unknown) | Ivermectin | Accidental exposure; Incorrect route of drug administration; No sign | — |
| — | Sheep | Sheep (other) | Cloprostenol 263 Inj Cattle | INEFFECTIVE, ESTRUS SYNCHRONIZ | Outcome Unknown |
| — | Sheep | Santa Cruz, Dorper | Isoflurane | Death; Pulmonary haemorrhage; Pulmonary oedema; Pulmonary congestion | Euthanized |
| — | Sheep | Suffolk sheep | Oxytetracycline Anhydrous | Death; Anaphylaxis | Died |
| — | Sheep | Sheep (unknown) | Flunixin | DEATH-SLAUGHTERED; Injection site reaction NOS; Residues in meat/offal | Died |
| — | Sheep | Sheep (unknown) | Florfenicol | Residues in meat/offal; DEATH-SLAUGHTERED | Died |
| — | Sheep | Sheep (unknown) | Flunixin Meglumine Injectable | Respiratory distress; Cough; Blood clot | Recovered/Normal |
| — | Sheep | Dorset Down | Ampicillin Trihydrate | Intrauterine death; Premature birth; Decreased body temperature; Anorexia; Un... | Died; Euthanized |
| — | Sheep | Sheep (unknown) | Ivermectin 0.08% Oral Liquid | Digestive tract disorder NOS; INEFFECTIVE, WORMS NOS | Outcome Unknown |
| — | Sheep | Sheep (other) | Eprinomectin | INEFFECTIVE, NEMATODES; Drug administration error | Outcome Unknown |
Frequently Asked Questions
Contact your veterinarian immediately. If the reaction is severe — difficulty breathing, seizures, collapse, or severe swelling — seek emergency veterinary care right away. After your pet is stabilized, report the adverse event to the FDA through safetyreporting.hhs.gov or by calling 1-888-FDA-VETS (1-888-332-8387). Reporting helps the FDA identify safety issues that can lead to label changes or product recalls.
Dogs account for the majority of adverse event reports, followed by cats. This reflects both the larger pet population and wider range of medications for these species. Flea and tick products, pain medications (NSAIDs), and heartworm preventives are among the product categories with the highest report counts across all species.
Not necessarily. A drug used by millions of pets will have more reports in absolute numbers than a niche product, even if the actual rate of adverse events is lower. The FDA uses these reports as one of many tools to evaluate drug safety, looking for patterns and statistical signals rather than raw counts alone. Always consult your veterinarian before changing any medication.