Browse Pet Safety Reports

1,493 FDA adverse event reports for pets.

FDA Veterinary Adverse Event Database

Browse 1,493 adverse event reports collected by the FDA's Center for Veterinary Medicine. Each report includes the animal species, breed, drug or product involved, observed reactions, and outcome. Reports flagged as "serious" involve death, life-threatening conditions, or hospitalization. Use the filters to narrow results by species, outcome severity, or keyword. Note that a higher number of reports does not necessarily indicate a less safe product — widely prescribed drugs naturally accumulate more reports.

Pet Adverse Event Reports

Browse 1,493 FDA veterinary adverse event reports for Other.

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Date Species Breed Drug Reaction Outcome
Jun 8, 2000 Other Unknown Selamectin Lack of efficacy - NOS; Tubes, Abnormal
Jun 8, 2000 Other Unknown Selamectin Lack of efficacy - NOS
Jun 7, 2000 Other Unknown Tiletamine, Zolazepam Mydriasis; Hyperexcitation; Recovery prolonged
Jun 7, 2000 Other Unknown Selamectin Lack of efficacy - NOS
Jun 6, 2000 Other Unknown Selamectin Lack of efficacy - NOS
Jun 6, 2000 Other Unknown Selamectin Application site alopecia
Jun 5, 2000 Other Unknown Selamectin Lack of efficacy - NOS
Jun 5, 2000 Other Unknown Selamectin Lack of efficacy - NOS
Jun 2, 2000 Other Unknown Selamectin Lack of efficacy (ectoparasite) - flea
Jun 1, 2000 Other Unknown Butorphanol Tartrate INEFFECTIVE, ANESTHESIA
Jun 1, 2000 Other Unknown Selamectin Lack of efficacy (ectoparasite) - flea
Jun 1, 2000 Other Unknown Selamectin Lack of efficacy - NOS
May 31, 2000 Other Unknown Selamectin Lack of efficacy - NOS
May 31, 2000 Other Unknown Selamectin Lack of efficacy - NOS
May 30, 2000 Other Unknown Selamectin Application site alopecia
May 30, 2000 Other Unknown Selamectin Lack of efficacy (ectoparasite) - flea
May 30, 2000 Other Unknown Selamectin Lack of efficacy (ectoparasite) - flea
May 29, 2000 Other Unknown Selamectin Lack of efficacy - NOS; Vomiting
May 28, 2000 Other Unknown Carprofen No sign; Accidental exposure
May 25, 2000 Other Unknown Selamectin Lack of efficacy - NOS
May 25, 2000 Other Unknown Selamectin Lack of efficacy - NOS
May 24, 2000 Other Unknown Selamectin Lack of efficacy (ectoparasite) - flea; Lack of efficacy (ectoparasite) - tic...
May 23, 2000 Other Unknown Selamectin Depression
May 20, 2000 Other Unknown Selamectin Vomiting
May 19, 2000 Other Unknown Selamectin Lack of efficacy (ectoparasite) - flea
May 18, 2000 Other Unknown Selamectin Lack of efficacy - NOS
May 18, 2000 Other Unknown Selamectin Lack of efficacy (ectoparasite) - flea
May 17, 2000 Other Unknown Carprofen Accidental exposure
May 17, 2000 Other Unknown Selamectin Lack of efficacy (ectoparasite) - flea; Lack of efficacy (ectoparasite) - tic...
May 16, 2000 Other Unknown Selamectin Lack of efficacy (ectoparasite) - tick NOS
May 15, 2000 Other Unknown Ketamine Hydrochloride INEFFECTIVE, ANESTHESIA
May 15, 2000 Other Unknown Selamectin Lack of efficacy (ectoparasite) - flea
May 15, 2000 Other Unknown Selamectin Lack of efficacy (ectoparasite) - flea
May 10, 2000 Other Unknown Selamectin Lack of efficacy (ectoparasite) - flea; Lack of efficacy (ectoparasite) - tic...
May 10, 2000 Other Unknown Selamectin Lack of efficacy (ectoparasite) - flea; Lack of efficacy (ectoparasite) - tic...
May 9, 2000 Other Unknown Selamectin Lack of efficacy (ectoparasite) - flea
May 8, 2000 Other Unknown Selamectin Lack of efficacy (ectoparasite) - flea
May 5, 2000 Other Unknown Selamectin Lack of efficacy (ectoparasite) - flea
May 2, 2000 Other Unknown Selamectin Fever; Anorexia; Depression
May 1, 2000 Other Unknown Betamethasone Valerate, Clotrimazole,... Unclassifiable adverse event
May 1, 2000 Other Unknown Selamectin Skin hyperaemia; Lack of efficacy (ectoparasite) - flea; Pruritus
Apr 29, 2000 Other Unknown Water, Dextrose, Sodium Chloride, Sod... Injection site pain; Anorexia; Fever; Depression; Death; Injection site necrosis Died
Apr 27, 2000 Other Unknown Selamectin Lack of efficacy (ectoparasite) - flea
Apr 27, 2000 Other Unknown Selamectin Lack of efficacy (ectoparasite) - flea; Lack of efficacy (ectoparasite) - tic...
Apr 25, 2000 Other Unknown Selamectin Lack of efficacy - NOS
Apr 24, 2000 Other Unknown Selamectin Lack of efficacy (ectoparasite) - tick NOS
Apr 19, 2000 Other Unknown Tiletamine, Zolazepam INEFFECTIVE, ANESTHESIA
Apr 19, 2000 Other Unknown Selamectin Lack of efficacy (ectoparasite) - tick NOS
Apr 17, 2000 Other Unknown Selamectin Lack of efficacy - NOS
Apr 17, 2000 Other Unknown Selamectin Lack of efficacy (ectoparasite) - tick NOS

Frequently Asked Questions

Contact your veterinarian immediately. If the reaction is severe — difficulty breathing, seizures, collapse, or severe swelling — seek emergency veterinary care right away. After your pet is stabilized, report the adverse event to the FDA through safetyreporting.hhs.gov or by calling 1-888-FDA-VETS (1-888-332-8387). Reporting helps the FDA identify safety issues that can lead to label changes or product recalls.

Dogs account for the majority of adverse event reports, followed by cats. This reflects both the larger pet population and wider range of medications for these species. Flea and tick products, pain medications (NSAIDs), and heartworm preventives are among the product categories with the highest report counts across all species.

Not necessarily. A drug used by millions of pets will have more reports in absolute numbers than a niche product, even if the actual rate of adverse events is lower. The FDA uses these reports as one of many tools to evaluate drug safety, looking for patterns and statistical signals rather than raw counts alone. Always consult your veterinarian before changing any medication.