Browse Pet Safety Reports

16,698 FDA adverse event reports for pets.

FDA Veterinary Adverse Event Database

Browse 16,698 adverse event reports collected by the FDA's Center for Veterinary Medicine. Each report includes the animal species, breed, drug or product involved, observed reactions, and outcome. Reports flagged as "serious" involve death, life-threatening conditions, or hospitalization. Use the filters to narrow results by species, outcome severity, or keyword. Note that a higher number of reports does not necessarily indicate a less safe product, widely prescribed drugs naturally accumulate more reports.

Pet Adverse Event Reports

Browse 16,698 FDA veterinary adverse event reports for Human.

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Date Species Breed Drug Reaction Outcome
Apr 22, 2012 Human Unknown Tilmicosin Phosphate Other abnormal test result NOS; Accidental exposure; Elevated creatine-kinase... Outcome Unknown
Apr 22, 2012 Human Unknown Mercaptobenzothiazole Unclassifiable adverse event; Accidental exposure; Accidental drug intake by ... -
Apr 22, 2012 Human Unknown Tilmicosin Phosphate Tachycardia; High blood pressure; Accidental exposure Recovered/Normal
Apr 20, 2012 Human Unknown Doramectin Unclassifiable adverse event; Unclassifiable adverse event; Accidental exposu... -
Apr 20, 2012 Human Unknown Toceranib Phosphate Unclassifiable adverse event; Unclassifiable adverse event; Accidental exposu... -
Apr 19, 2012 Human Unknown Spinosad; Milbemycin Oxime Increased heart rate; Diarrhoea; Headache; Stomach cramp; Tiredness; Accident... Outcome Unknown
Apr 19, 2012 Human Unknown Milbemycin Oxime; Lufenuron Light headedness Recovered/Normal
Apr 18, 2012 Human Unknown Spinosad Headache; Accidental exposure Outcome Unknown
Apr 18, 2012 Human Unknown Xylazine Coma; Suicide attempt Outcome Unknown
Apr 17, 2012 Human Unknown Imidacloprid; Moxidectin Eye disorder NOS (for photophobia see 'neurological'); Accidental exposure Recovered/Normal
Apr 17, 2012 Human Unknown Emodepside; Praziquantel Diarrhoea; Nausea; Musculoskeletal pain; Feelings of weakness; Tiredness; Vom... Outcome Unknown
Apr 17, 2012 Human Unknown Spinosad; Milbemycin Oxime Loose stool; Accidental exposure Outcome Unknown
Apr 17, 2012 Human Unknown Ivermectin 0.5% Pour-On Nausea Recovered/Normal
Apr 16, 2012 Human Unknown Bacitracin Methylene Disalicylate Unclassifiable adverse event; Accidental exposure; Sinusitis -
Apr 16, 2012 Human Unknown Gamithromycin 15% Injection Injection site reaction NOS; Accidental exposure Outcome Unknown
Apr 15, 2012 Human Unknown Tresaderm Dermatological Solution Eye irritation Recovered/Normal
Apr 14, 2012 Human Unknown Moxidectin Unclassifiable adverse event; Accidental exposure; Dyspnoea; Paraesthesia; Mu... -
Apr 14, 2012 Human Unknown Moxidectin; Imidacloprid Diarrhoea; Migraine; Vomiting Recovered/Normal
Apr 13, 2012 Human Unknown Dinoprost Tromethamine Menstrual cramp Recovered/Normal
Apr 12, 2012 Human Unknown Tiletamine, Zolazepam Unclassifiable adverse event; Accidental exposure; Eye irritation; Eye redness -
Apr 11, 2012 Human Unknown Maropitant Unclassifiable adverse event; Accidental exposure; Accidental drug intake by ... -
Apr 11, 2012 Human Unknown Ivermectin 136Mcg, Pyrantel 114Mg Anxious state of mind Outcome Unknown
Apr 10, 2012 Human Unknown Isoflurane No sign; Unclassifiable adverse event; Accidental exposure -
Apr 9, 2012 Human Unknown Tilmicosin Phosphate Increased heart rate; Chest tightness; Nausea; Tiredness; General illness; Ac... Outcome Unknown
Apr 9, 2012 Human Unknown Selamectin Unclassifiable adverse event; Unclassifiable adverse event; Accidental exposu... -
Apr 8, 2012 Human Unknown Pentobarbital Sodium, Phenytoin Sodium Injection site numbness; Injection site pain; Injection site swelling Outcome Unknown
Apr 7, 2012 Human Unknown Ceftiofur Unclassifiable adverse event; Unclassifiable adverse event; Accidental exposu... -
Apr 6, 2012 Human Unknown Selamectin Unclassifiable adverse event; Accidental exposure; Eye pain; Odor, Abnormal -
Apr 6, 2012 Human Unknown Milbemycin Oxime; Lufenuron Digestive tract disorder NOS Recovered/Normal
Apr 5, 2012 Human Unknown Gamithromycin Unclassifiable adverse event; Unclassifiable adverse event; Accidental exposu... -
Apr 5, 2012 Human Unknown Enrofloxacin Injection site lesion; Injection site pain Outcome Unknown
Apr 3, 2012 Human Unknown Spinosad Diarrhoea Recovered/Normal
Apr 2, 2012 Human Unknown Spinosad; Milbemycin Oxime Hives (see also 'Skin'); Rash Outcome Unknown
Apr 2, 2012 Human Unknown Clindamycin Hydrochloride Liquid 25 Mg Nausea; Odor, Abnormal Recovered/Normal
Apr 2, 2012 Human Unknown Moxidectin; Imidacloprid Burning sensation (skin); Generalised rash; Skin inflammation NOS; Pruritus; ... Recovered/Normal
Apr 1, 2012 Human Unknown Tresaderm Dermatological Solution Eye irritation Recovered/Normal
Apr 1, 2012 Human Unknown Tulathromycin Unclassifiable adverse event; Unclassifiable adverse event; Accidental exposu... -
Apr 1, 2012 Human Unknown Selamectin Unclassifiable adverse event; Unclassifiable adverse event; Unclassifiable ad... -
Mar 30, 2012 Human Unknown Spinosad Stomach upset Recovered/Normal
Mar 30, 2012 Human Unknown Ivermectin 68Mcg, Pyrantel Pamoate 57... Nausea Outcome Unknown
Mar 29, 2012 Human Unknown Selamectin Unclassifiable adverse event; Accidental exposure; Anaphylaxis; Urticaria; Pr... -
Mar 27, 2012 Human Unknown Spinosad; Spinosad Bruising; Erythema (for urticaria see Immune SOC) Outcome Unknown
Mar 23, 2012 Human Unknown Oxytetracycline Hydrochloride Unclassifiable adverse event; Accidental exposure; Eye irritation; Conjunctiv... -
Mar 22, 2012 Human Unknown Ceftiofur Unclassifiable adverse event; Unclassifiable adverse event; Accidental exposu... -
Mar 22, 2012 Human Unknown Imidacloprid; Moxidectin Paraesthesia; Accidental exposure Outcome Unknown
Mar 22, 2012 Human Unknown Tulathromycin Unclassifiable adverse event; Unclassifiable adverse event; Accidental exposu... -
Mar 21, 2012 Human Unknown Ivermectin Unclassifiable adverse event; Accidental exposure; Eye irritation -
Mar 21, 2012 Human Unknown Ivermectin 272Mcg, Pyrantel 227Mg Digestive tract disorder NOS; Blood in vomit; Nasal bleeding Recovered/Normal
Mar 20, 2012 Human Unknown Pentobarbital Sodium, Phenytoin Sodium Muscle spasm NOS; Tongue paraesthesia; Burning sensation (skin); Generalised ... Recovered/Normal
Mar 19, 2012 Human Unknown Enrofloxacin Hives (see also 'Skin'); Rash; Bone and joint disorder NOS; Joint pain NOS; A... Recovered/Normal

Frequently Asked Questions

Contact your veterinarian immediately. If the reaction is severe, difficulty breathing, seizures, collapse, or severe swelling, seek emergency veterinary care right away. After your pet is stabilized, report the adverse event to the FDA through safetyreporting.hhs.gov or by calling 1-888-FDA-VETS (1-888-332-8387). Reporting helps the FDA identify safety issues that can lead to label changes or product recalls.

Dogs account for the majority of adverse event reports, followed by cats. This reflects both the larger pet population and wider range of medications for these species. Flea and tick products, pain medications (NSAIDs), and heartworm preventives are among the product categories with the highest report counts across all species.

Not necessarily. A drug used by millions of pets will have more reports in absolute numbers than a niche product, even if the actual rate of adverse events is lower. The FDA uses these reports as one of many tools to evaluate drug safety, looking for patterns and statistical signals rather than raw counts alone. Always consult your veterinarian before changing any medication.