Browse Pet Safety Reports

1,493 FDA adverse event reports for pets.

FDA Veterinary Adverse Event Database

Browse 1,493 adverse event reports collected by the FDA's Center for Veterinary Medicine. Each report includes the animal species, breed, drug or product involved, observed reactions, and outcome. Reports flagged as "serious" involve death, life-threatening conditions, or hospitalization. Use the filters to narrow results by species, outcome severity, or keyword. Note that a higher number of reports does not necessarily indicate a less safe product, widely prescribed drugs naturally accumulate more reports.

Pet Adverse Event Reports

Browse 1,493 FDA veterinary adverse event reports for Other.

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Date Species Breed Drug Reaction Outcome
Aug 26, 2003 Other Unknown Ketamine Hydrochloride Ataxia; Confusion; Recovery prolonged -
Aug 13, 2003 Other Unknown Ractopamine Accidental exposure; Residues in meat/offal; RESIDUE, URINE -
Aug 3, 2003 Other Unknown Carprofen Injection site abscess; Death by euthanasia Died
Aug 1, 2003 Other Unknown Carprofen Death; Injection site abscess Died
Jul 29, 2003 Other Unknown Pentobarbital, Phenytoin Abnormal breathing; Hyperactivity; INEFFECTIVE, EUTHANASIA Died
Jul 23, 2003 Other Unknown Tiletamine, Zolazepam INEFFECTIVE, ANESTHESIA -
Jul 23, 2003 Other Unknown Doxorubicin No sign -
Jul 18, 2003 Other Unknown Ketamine Hydrochloride INEFFECTIVE, ANESTHESIA -
Jul 16, 2003 Other Unknown Oxytetracycline Hydrochloride Lack of efficacy (bacteria) - NOS; Death by euthanasia Died
Jul 8, 2003 Other Unknown Gentamicin Sulfate Depression -
Jul 2, 2003 Other Unknown Pentobarbital, Phenytoin INEFFECTIVE, EUTHANASIA Died
Jul 1, 2003 Other Unknown Xylazine INEFFECTIVE, SEDATION -
Jun 4, 2003 Other Unknown Tilmicosin Phosphate Paddling; Agitation -
May 7, 2003 Other Unknown Oxfendazole Lack of efficacy (endoparasite) - hookworm; Lack of efficacy (endoparasite) -... Died
May 7, 2003 Other Unknown Ketamine Hydrochloride INEFFECTIVE, ANESTHESIA -
Apr 28, 2003 Other Unknown Isoflurane Apnoea; Cardiac arrest; Dyspnoea; Death Died
Apr 21, 2003 Other Unknown Ketamine Hydrochloride INEFFECTIVE, ANESTHESIA -
Mar 28, 2003 Other Unknown Chlorhexidine Scrotal oedema; Application site erythema; Swelling NOS; Skin abscess -
Mar 25, 2003 Other Unknown Ketamine Hydrochloride INEFFECTIVE, ANESTHESIA -
Feb 10, 2003 Other Unknown Ketamine Hydrochloride INEFFECTIVE, SEDATION -
Feb 4, 2003 Other Unknown Oxibendazole Loose stool -
Feb 4, 2003 Other Unknown Xylazine INEFFECTIVE, ANESTHESIA -
Dec 17, 2002 Other Unknown Famphur Malaise -
Dec 10, 2002 Other Unknown Tiletamine, Zolazepam Fever -
Nov 21, 2002 Other Unknown Albendazole Pneumonia; Death Died
Nov 20, 2002 Other Unknown Ketamine Hydrochloride INEFFECTIVE, ANESTHESIA -
Nov 13, 2002 Other Unknown Fluorometholone Death by euthanasia; Anorexia; Elevated alanine aminotransferase (ALT); Eleva... Died
Oct 25, 2002 Other Unknown Fenbendazole Death Died
Oct 23, 2002 Other Unknown Xylazine INEFFECTIVE, SEDATION -
Oct 13, 2002 Other Unknown Ketamine Hydrochloride INEFFECTIVE, ANESTHESIA -
Oct 1, 2002 Other Unknown Famphur Hypersalivation; Hypersalivation; Ataxia Died
Sep 20, 2002 Other Unknown Ketamine Hydrochloride INEFFECTIVE, SEDATION -
Aug 30, 2002 Other Unknown Tiletamine, Zolazepam Death Died
Aug 15, 2002 Other Unknown Tiletamine, Zolazepam INEFFECTIVE, ANESTHESIA; Potency, Low -
Aug 13, 2002 Other Unknown Tiletamine, Zolazepam INEFFECTIVE, ANESTHESIA -
Jul 18, 2002 Other Unknown Ketamine Hydrochloride INEFFECTIVE, ANESTHESIA -
Jul 9, 2002 Other Unknown Stanozolol Hypercalcaemia -
May 29, 2002 Other Unknown Selamectin Lack of efficacy (ectoparasite) - flea -
Apr 30, 2002 Other Unknown Ivermectin, Pyrantel Lack of efficacy - NOS -
Apr 9, 2002 Other Unknown Ivermectin Bradycardia; Anaphylaxis; Hypothermia -
Apr 1, 2002 Other Unknown Ketamine Hydrochloride INEFFECTIVE, ANESTHESIA -
Apr 1, 2002 Other Unknown Ketamine Hydrochloride Cardiac arrest; Death Died
Mar 27, 2002 Other Unknown Ketamine Hydrochloride INEFFECTIVE, ANESTHESIA -
Mar 7, 2002 Other Unknown Carprofen No sign; Accidental exposure -
Feb 20, 2002 Other Unknown Ketamine Hydrochloride INEFFECTIVE, SEDATION -
Feb 18, 2002 Other Unknown Pentobarbital, Phenytoin INEFFECTIVE, EUTHANASIA Died
Jan 24, 2002 Other Unknown Amitraz Anorexia; Diarrhoea; Death; Dehydration; Eyelid oedema Died
Jan 22, 2002 Other Unknown Amoxicillin Injection site pain -
Jan 16, 2002 Other Unknown Glycosaminoglycan Polysulfate Immune mediated haemolytic anaemia -
Jan 15, 2002 Other Unknown Ketamine Hydrochloride INEFFECTIVE, ANESTHESIA -

Frequently Asked Questions

Contact your veterinarian immediately. If the reaction is severe, difficulty breathing, seizures, collapse, or severe swelling, seek emergency veterinary care right away. After your pet is stabilized, report the adverse event to the FDA through safetyreporting.hhs.gov or by calling 1-888-FDA-VETS (1-888-332-8387). Reporting helps the FDA identify safety issues that can lead to label changes or product recalls.

Dogs account for the majority of adverse event reports, followed by cats. This reflects both the larger pet population and wider range of medications for these species. Flea and tick products, pain medications (NSAIDs), and heartworm preventives are among the product categories with the highest report counts across all species.

Not necessarily. A drug used by millions of pets will have more reports in absolute numbers than a niche product, even if the actual rate of adverse events is lower. The FDA uses these reports as one of many tools to evaluate drug safety, looking for patterns and statistical signals rather than raw counts alone. Always consult your veterinarian before changing any medication.