Browse Pet Safety Reports

1,493 FDA adverse event reports for pets.

FDA Veterinary Adverse Event Database

Browse 1,493 adverse event reports collected by the FDA's Center for Veterinary Medicine. Each report includes the animal species, breed, drug or product involved, observed reactions, and outcome. Reports flagged as "serious" involve death, life-threatening conditions, or hospitalization. Use the filters to narrow results by species, outcome severity, or keyword. Note that a higher number of reports does not necessarily indicate a less safe product, widely prescribed drugs naturally accumulate more reports.

Pet Adverse Event Reports

Browse 1,493 FDA veterinary adverse event reports for Other.

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Date Species Breed Drug Reaction Outcome
Aug 10, 2004 Other Unknown Calcium Death; Behavioural disorder NOS Died
Aug 3, 2004 Other Unknown Ketamine Hydrochloride Recovery prolonged; Hypothermia -
Jul 27, 2004 Other Unknown Oxytetracycline, Polymyxin B Sulfate Lack of efficacy (bacteria) - NOS; Ocular discharge -
Jun 25, 2004 Other Unknown Moxidectin Gel/Paste, Abnormal -
Jun 15, 2004 Other Unknown Ketamine Hydrochloride Death by euthanasia; INEFFECTIVE, ANESTHESIA Died
Jun 15, 2004 Other Unknown Monensin No sign; Inappropriate preparation of medication -
Jun 11, 2004 Other Unknown Orbifloxacin Lack of efficacy (bacteria) - NOS -
Jun 8, 2004 Other Unknown Ketamine Hydrochloride INEFFECTIVE, ANESTHESIA -
Jun 6, 2004 Other Unknown Ivermectin Convulsion; Ataxia; Death; Confusion Died
Jun 1, 2004 Other Unknown Ivermectin Dysphagia; Death; Weakness Died
May 24, 2004 Other Unknown Tiletamine, Zolazepam INEFFECTIVE, ANESTHESIA -
May 17, 2004 Other Unknown Ketamine Hydrochloride INEFFECTIVE, ANESTHESIA -
May 7, 2004 Other Unknown Ketamine Hydrochloride Death Died
May 6, 2004 Other Unknown Pentobarbital, Phenytoin INEFFECTIVE, DELAYED EFFECT; INEFFECTIVE, EUTHANASIA Died
May 4, 2004 Other Unknown Ketamine Hydrochloride INEFFECTIVE, ANESTHESIA -
Apr 29, 2004 Other Unknown Ampicillin Trihydrate Injection site swelling -
Apr 27, 2004 Other Unknown Ketoprofen Coagulopathy -
Apr 23, 2004 Other Unknown Tiletamine, Zolazepam INEFFECTIVE, ANESTHESIA; Hyperexcitation -
Apr 15, 2004 Other Unknown Sevoflurane Cardiac arrest; Apnoea; Haemoptysis; Death; PR-HEART, LESION(S) Died
Apr 8, 2004 Other Unknown Xylazine INEFFECTIVE, ANESTHESIA -
Mar 31, 2004 Other Unknown Ketamine Hydrochloride INEFFECTIVE, ANESTHESIA -
Mar 30, 2004 Other Unknown Pentobarbital, Phenytoin INEFFECTIVE, EUTHANASIA Died
Mar 12, 2004 Other Unknown Ketamine Hydrochloride Prolonged anaesthesia; Apnoea; Recovery prolonged -
Mar 10, 2004 Other Unknown Ivermectin Skin scab; Injection site infection; Injection site mass -
Mar 9, 2004 Other Unknown Tiletamine, Zolazepam INEFFECTIVE, ANESTHESIA -
Mar 8, 2004 Other Unknown Mitotane Unclassifiable adverse event -
Feb 27, 2004 Other Unknown Fenbendazole Infertility NOS -
Feb 20, 2004 Other Unknown Ketamine Hydrochloride INEFFECTIVE, ANESTHESIA -
Feb 20, 2004 Other Unknown Sevoflurane Death by euthanasia Died
Feb 17, 2004 Other Unknown Glycopyrrolate INEFFECTIVE, ANESTHESIA -
Jan 17, 2004 Other Unknown Ketamine Hydrochloride INEFFECTIVE, ANESTHESIA; Potency, Low -
Jan 14, 2004 Other Unknown Tiletamine, Zolazepam INEFFECTIVE, ANESTHESIA -
Jan 9, 2004 Other Unknown Monensin Diarrhoea; Dyspnoea; Death; Anorexia; Recumbency Died
Jan 7, 2004 Other Unknown Butorphanol Tartrate No sign -
Jan 6, 2004 Other Unknown Butorphanol Tartrate Constipation; Flatulence; Anorexia; Dehydration; Gastric bloat; Depression -
Dec 29, 2003 Other Unknown Cyclosporine Skin sore -
Dec 10, 2003 Other Unknown Glycopyrrolate Fever -
Dec 10, 2003 Other Unknown Butorphanol Tartrate Fever -
Dec 5, 2003 Other Unknown Butorphanol Tartrate Injection site pain -
Nov 6, 2003 Other Unknown Monensin Accidental exposure; Inappropriate preparation of medication; Death Died
Nov 1, 2003 Other Unknown Tiletamine, Zolazepam INEFFECTIVE, ANESTHESIA -
Oct 16, 2003 Other Unknown Ketamine Hydrochloride Tachycardia; Apprehension -
Oct 14, 2003 Other Unknown Tiletamine, Zolazepam INEFFECTIVE, ANESTHESIA -
Sep 16, 2003 Other Unknown Tiletamine, Zolazepam INEFFECTIVE, ANESTHESIA -
Sep 15, 2003 Other Unknown Ketamine Hydrochloride INEFFECTIVE, ANESTHESIA -
Sep 15, 2003 Other Unknown Butorphanol Tartrate INEFFECTIVE, ANESTHESIA -
Sep 10, 2003 Other Unknown Pyrantel Pamoate INEFFECTIVE, ASCARIDS NOS; Lack of efficacy (endoparasite) - hookworm -
Aug 28, 2003 Other Unknown Ketamine Hydrochloride Death Died
Aug 28, 2003 Other Unknown Nitazoxanide Death Died
Aug 28, 2003 Other Unknown Ketamine Hydrochloride Death; Unclassifiable adverse event Died

Frequently Asked Questions

Contact your veterinarian immediately. If the reaction is severe, difficulty breathing, seizures, collapse, or severe swelling, seek emergency veterinary care right away. After your pet is stabilized, report the adverse event to the FDA through safetyreporting.hhs.gov or by calling 1-888-FDA-VETS (1-888-332-8387). Reporting helps the FDA identify safety issues that can lead to label changes or product recalls.

Dogs account for the majority of adverse event reports, followed by cats. This reflects both the larger pet population and wider range of medications for these species. Flea and tick products, pain medications (NSAIDs), and heartworm preventives are among the product categories with the highest report counts across all species.

Not necessarily. A drug used by millions of pets will have more reports in absolute numbers than a niche product, even if the actual rate of adverse events is lower. The FDA uses these reports as one of many tools to evaluate drug safety, looking for patterns and statistical signals rather than raw counts alone. Always consult your veterinarian before changing any medication.