Browse Pet Safety Reports

16,698 FDA adverse event reports for pets.

FDA Veterinary Adverse Event Database

Browse 16,698 adverse event reports collected by the FDA's Center for Veterinary Medicine. Each report includes the animal species, breed, drug or product involved, observed reactions, and outcome. Reports flagged as "serious" involve death, life-threatening conditions, or hospitalization. Use the filters to narrow results by species, outcome severity, or keyword. Note that a higher number of reports does not necessarily indicate a less safe product, widely prescribed drugs naturally accumulate more reports.

Pet Adverse Event Reports

Browse 16,698 FDA veterinary adverse event reports for Human.

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Date Species Breed Drug Reaction Outcome
Dec 28, 2014 Human Unknown Moxidectin Hand and arm swollen; Pain NOS; Injection site reaction NOS; Accidental exposure Recovered/Normal
Dec 26, 2014 Human Unknown Tilmicosin Phosphate Application site rash; Chest tightness; Inappropriate preparation of medication Recovered/Normal
Dec 24, 2014 Human Unknown Clindamycin Abdominal discomfort; Bad taste; Nervousness Recovered/Normal
Dec 24, 2014 Human Unknown Tilmicosin Phosphate High blood pressure; Thoracic pain; Accidental exposure Recovered with Sequela
Dec 22, 2014 Human Unknown Pentobarbital Sodium, Phenytoin Sodium Bad taste Recovered/Normal
Dec 19, 2014 Human Unknown Oxytetracycline Pain NOS; Swelling NOS Recovered/Normal
Dec 18, 2014 Human Unknown Ceftiofur Crystalline Free Acid Loss of consciousness; Chest discomfort NOS; Heart pounding Outcome Unknown
Dec 16, 2014 Human Unknown Eprinomectin 5 Mg/Ml Pour-On Solution Ocular burn Recovered/Normal
Dec 15, 2014 Human Unknown Nitenpyram Erythematous rash; Skin irritation Recovered/Normal
Dec 15, 2014 Human Unknown Nitenpyram Nausea; Accidental exposure Recovered/Normal
Dec 14, 2014 Human Unknown Tilmicosin Phosphate Injection site bleeding; Accidental exposure Recovered/Normal
Dec 14, 2014 Human Unknown Selamectin Atrial fibrillation Recovered/Normal
Dec 13, 2014 Human Unknown Tilmicosin Phosphate Injection site pain; Injection site numbness; Accidental exposure Recovered/Normal
Dec 12, 2014 Human Unknown Spinosad Stomach upset Recovered/Normal
Dec 12, 2014 Human Unknown Maropitant Citrate Injection site erythema; Injection site oedema; Injection site pain; Injectio... Recovered/Normal
Dec 11, 2014 Human Unknown Sevoflurane Unclassifiable adverse event; Accidental exposure; Abortion; Premature birth Outcome Unknown
Dec 10, 2014 Human Unknown Spinosad; Milbemycin Oxime Cough; Eye itching Outcome Unknown
Dec 7, 2014 Human Unknown Imidacloprid; Moxidectin Eye irritation; Red eye; Accidental exposure Outcome Unknown
Dec 7, 2014 Human Unknown Tilmicosin Phosphate Emesis (multiple); Diarrhoea; General illness; Increased heart rate; High blo... Recovered/Normal
Dec 5, 2014 Human Unknown Tulathromycin Injection site reaction NOS Recovered/Normal
Dec 2, 2014 Human Unknown Selamectin Injection site reaction NOS; Accidental exposure Outcome Unknown
Dec 1, 2014 Human Unknown Phytosphingosine - Salicyloyl (0.05%)... Pruritus; Dry skin; Skin lesion NOS; Skin irritation Recovered with Sequela
Dec 1, 2014 Human Unknown Selamectin Rash Ongoing
Dec 1, 2014 Human Unknown Florfenicol/Flunixin Inj-Triac Injection site bleeding; Injection site swelling; General pain (see other SOC... Outcome Unknown
Nov 26, 2014 Human Unknown Spinosad Stomach upset; Stomach pain Recovered with Sequela
Nov 24, 2014 Human Unknown Ivermectin 1% Injection Injection site bruising; Injection site swelling; Skin lesion NOS; Injection ... Outcome Unknown
Nov 24, 2014 Human Unknown Mercaptobenzothiazole Unclassifiable adverse event; Unclassifiable adverse event; Accidental drug i... -
Nov 23, 2014 Human Unknown Phenylpropanolamine Hcl Throat irritation; Accidental exposure Recovered/Normal
Nov 23, 2014 Human Unknown Nitenpyram; Nitenpyram Digestive tract disorder NOS; Stomach pain; Accidental exposure Recovered/Normal
Nov 21, 2014 Human Unknown Toceranib Phosphate Breast disorder NOS Outcome Unknown
Nov 19, 2014 Human Unknown Cefovecin Injection site lump; Reddening of the skin; Accidental exposure Outcome Unknown
Nov 18, 2014 Human Unknown Afoxolaner Hives (see also 'Skin'); Allergic reaction Outcome Unknown
Nov 18, 2014 Human Unknown Tresaderm Dermatological Solution Eye numbness; Eye irritation Recovered/Normal
Nov 17, 2014 Human Unknown Selamectin Application site irritation; Eye irritation; Eye redness; Accidental exposure Outcome Unknown
Nov 14, 2014 Human Unknown Tilmicosin Phosphate Pain NOS; Injection site pain; Accidental exposure Outcome Unknown
Nov 13, 2014 Human Unknown Imidacloprid; Moxidectin Localised numbness (see also application site SOC); Respiratory tract disorde... Outcome Unknown
Nov 13, 2014 Human Unknown Spinosad; Milbemycin Oxime Emesis; Nausea; Feeling anxious Outcome Unknown
Nov 12, 2014 Human Unknown Ceftiofur Crystalline Free Acid Tingling sensation; Tongue disorder NOS; Accidental exposure Outcome Unknown
Nov 11, 2014 Human Unknown Selamectin Tongue paraesthesia; Application site numbness Recovered/Normal
Nov 11, 2014 Human Unknown Toceranib Phosphate Elevated aspartate aminotransferase (AST); Elevated alanine aminotransferase ... Ongoing
Nov 10, 2014 Human Unknown Tulathromycin Injection site oedema Outcome Unknown
Nov 9, 2014 Human Unknown Copper Naphthenate Unclassifiable adverse event; Accidental exposure; Eye irritation; Eye redness -
Nov 8, 2014 Human Unknown Gonadorelindiacetate Tetrahydrate Inj... Female reproductive tract disorder NOS Outcome Unknown
Nov 8, 2014 Human Unknown Lasalocid Sodium Hives (see also 'Skin') Recovered/Normal
Nov 6, 2014 Human Unknown Tulathromycin Eye irritation; Nausea Outcome Unknown
Nov 6, 2014 Human Unknown Selamectin Uncoded sign; Accidental exposure Outcome Unknown
Nov 6, 2014 Human Unknown Ivermectin 0.5% Pour-On Bad taste Outcome Unknown
Nov 5, 2014 Human Unknown Gamithromycin 15% Injection Nausea; Dizziness; Retching; Nervousness Recovered/Normal
Nov 3, 2014 Human Unknown Trilostane Dizziness; Headache; Diarrhoea; Accidental exposure Outcome Unknown
Nov 3, 2014 Human Unknown Spinosad; Milbemycin Oxime Rash; Itching; Hives (see also 'Skin') Outcome Unknown

Frequently Asked Questions

Contact your veterinarian immediately. If the reaction is severe, difficulty breathing, seizures, collapse, or severe swelling, seek emergency veterinary care right away. After your pet is stabilized, report the adverse event to the FDA through safetyreporting.hhs.gov or by calling 1-888-FDA-VETS (1-888-332-8387). Reporting helps the FDA identify safety issues that can lead to label changes or product recalls.

Dogs account for the majority of adverse event reports, followed by cats. This reflects both the larger pet population and wider range of medications for these species. Flea and tick products, pain medications (NSAIDs), and heartworm preventives are among the product categories with the highest report counts across all species.

Not necessarily. A drug used by millions of pets will have more reports in absolute numbers than a niche product, even if the actual rate of adverse events is lower. The FDA uses these reports as one of many tools to evaluate drug safety, looking for patterns and statistical signals rather than raw counts alone. Always consult your veterinarian before changing any medication.