Browse Pet Safety Reports
1,493 FDA adverse event reports for pets.
FDA Veterinary Adverse Event Database
Browse 1,493 adverse event reports collected by the FDA's Center for Veterinary Medicine. Each report includes the animal species, breed, drug or product involved, observed reactions, and outcome. Reports flagged as "serious" involve death, life-threatening conditions, or hospitalization. Use the filters to narrow results by species, outcome severity, or keyword. Note that a higher number of reports does not necessarily indicate a less safe product — widely prescribed drugs naturally accumulate more reports.
Pet Adverse Event Reports
Browse 1,493 FDA veterinary adverse event reports for Other.
| Date | Species | Breed | Drug | Reaction | Outcome |
|---|---|---|---|---|---|
| Apr 15, 1994 | Other | Unknown | Isoflurane | Death | Died |
| Mar 17, 1994 | Other | Unknown | Pentobarbital, Phenytoin | Lack of efficacy - NOS | Died |
| Mar 1, 1994 | Other | Unknown | Tiletamine, Zolazepam | INEFFECTIVE, ANESTHESIA | — |
| Feb 23, 1994 | Other | Unknown | Ketamine Hydrochloride | Uraemia; Convulsion; Fever; Peripheral nervous system disorder NOS | — |
| Feb 21, 1994 | Other | Unknown | Tiletamine, Zolazepam | INEFFECTIVE, ANESTHESIA | — |
| Feb 9, 1994 | Other | Unknown | Ketamine Hydrochloride | Cardiac arrest; Convulsion | — |
| Feb 8, 1994 | Other | Unknown | Tiletamine, Zolazepam | INEFFECTIVE, ANESTHESIA | — |
| Feb 8, 1994 | Other | Unknown | Ketamine Hydrochloride | INEFFECTIVE, ANESTHESIA | — |
| Feb 7, 1994 | Other | Unknown | Tiletamine, Zolazepam | Cardiac arrest; Apnoea; Death | Died |
| Dec 28, 1993 | Other | Unknown | Amoxicillin | Injection site pain | — |
| Dec 17, 1993 | Other | Unknown | Cefadroxil | Unclassifiable adverse event | — |
| Dec 17, 1993 | Other | Unknown | Cefadroxil | Defect Unknown/Not Specified | — |
| Dec 10, 1993 | Other | Unknown | Ketamine Hydrochloride | INEFFECTIVE, ANESTHESIA | — |
| Nov 19, 1993 | Other | Unknown | Pentobarbital, Phenytoin | INEFFECTIVE, EUTHANASIA | Died |
| Nov 19, 1993 | Other | Unknown | Pentobarbital, Phenytoin | INEFFECTIVE, EUTHANASIA | Died |
| Sep 16, 1993 | Other | Unknown | Chorionic Gonadotropin | INEFFECTIVE, OVULATION | — |
| Aug 31, 1993 | Other | Unknown | Ketamine Hydrochloride | INEFFECTIVE, ANESTHESIA | — |
| Jun 14, 1993 | Other | Unknown | Tiletamine, Zolazepam | Pulmonary congestion; PR-LUNG(S), LESION(S); Apnoea; Death | Died |
| Jun 10, 1993 | Other | Unknown | Bacitracin, Neomycin, Polymyxin B | Corneal ulcer | — |
| Jun 7, 1993 | Other | Unknown | Ketamine Hydrochloride | INEFFECTIVE, ANESTHESIA | — |
| May 26, 1993 | Other | Unknown | Pentobarbital, Phenytoin | Lack of efficacy - NOS | Died |
| May 26, 1993 | Other | Unknown | Pentobarbital, Phenytoin | Lack of efficacy - NOS | Died |
| May 4, 1993 | Other | Unknown | Ketamine Hydrochloride | INEFFECTIVE, ANESTHESIA | — |
| Feb 22, 1993 | Other | Unknown | Tiletamine, Zolazepam | INEFFECTIVE, ANESTHESIA; Death | Died |
| Jan 27, 1993 | Other | Unknown | Epsiprantel | Lack of efficacy (endoparasite) - tapeworm | — |
| Aug 31, 1992 | Other | Unknown | Ketamine Hydrochloride | INEFFECTIVE, ANESTHESIA | — |
| Jun 12, 1992 | Other | Unknown | Pentobarbital, Phenytoin | Lack of efficacy - NOS | — |
| Apr 16, 1992 | Other | Unknown | Tiletamine, Zolazepam | INEFFECTIVE, ANESTHESIA | — |
| Mar 23, 1992 | Other | Unknown | Acepromazine Maleate | Apnoea; Death | Died |
| Feb 10, 1992 | Other | Unknown | Tiletamine, Zolazepam | Lack of efficacy - NOS | — |
| Apr 23, 1991 | Other | Unknown | Ketamine Hydrochloride | Death | Died |
| Mar 12, 1991 | Other | Unknown | N-Butyl Chloride | Lack of efficacy - NOS | — |
| Oct 23, 1990 | Other | Unknown | Monensin | Death | Died |
| Jul 17, 1990 | Other | Unknown | Thiamylal | INEFFECTIVE, ANESTHESIA | — |
| Jul 17, 1990 | Other | Unknown | Thiamylal | Unclassifiable adverse event | — |
| Jul 10, 1990 | Other | Unknown | Ivermectin | Death; Stupor | Died |
| Jun 4, 1990 | Other | Unknown | Xylazine | INEFFECTIVE, ANESTHESIA | — |
| May 8, 1990 | Other | Unknown | Ivermectin | Bloody diarrhoea; Enteritis; Death | Died |
| May 4, 1990 | Other | Unknown | Ivermectin | Death | Died |
| Dec 1, 1989 | Other | Unknown | Methylprednisolone Acetate | Lack of efficacy - NOS | — |
| Dec 1, 1989 | Other | Unknown | Methylprednisolone Acetate | Lack of efficacy - NOS | — |
| Oct 31, 1989 | Other | Unknown | Fenbendazole | Death; Weight loss; PR-KIDNEY(S), LESION(S); PR-INTEST, LESION(S); Vomiting; ... | Died |
| Oct 20, 1989 | Other | Unknown | Fenbendazole | Lack of efficacy - NOS | — |
| Oct 6, 1989 | Other | Unknown | Amoxicillin | Injection site pain | — |
| Oct 6, 1989 | Other | Unknown | Amoxicillin | Injection site pain | — |
| Aug 1, 1989 | Other | Unknown | Xylazine | Lack of efficacy - NOS | — |
| Jun 2, 1989 | Other | Unknown | Pentobarbital, Phenytoin | Lack of efficacy - NOS | Died |
| Apr 6, 1989 | Other | Unknown | Tiletamine, Zolazepam | Death | Died |
| Feb 24, 1989 | Other | Unknown | Xylazine | INEFFECTIVE, SEDATION | — |
| Dec 7, 1988 | Other | Unknown | Ketamine Hydrochloride | INEFFECTIVE, ANESTHESIA | — |
Frequently Asked Questions
Contact your veterinarian immediately. If the reaction is severe — difficulty breathing, seizures, collapse, or severe swelling — seek emergency veterinary care right away. After your pet is stabilized, report the adverse event to the FDA through safetyreporting.hhs.gov or by calling 1-888-FDA-VETS (1-888-332-8387). Reporting helps the FDA identify safety issues that can lead to label changes or product recalls.
Dogs account for the majority of adverse event reports, followed by cats. This reflects both the larger pet population and wider range of medications for these species. Flea and tick products, pain medications (NSAIDs), and heartworm preventives are among the product categories with the highest report counts across all species.
Not necessarily. A drug used by millions of pets will have more reports in absolute numbers than a niche product, even if the actual rate of adverse events is lower. The FDA uses these reports as one of many tools to evaluate drug safety, looking for patterns and statistical signals rather than raw counts alone. Always consult your veterinarian before changing any medication.