Browse Pet Safety Reports
1,493 FDA adverse event reports for pets.
FDA Veterinary Adverse Event Database
Browse 1,493 adverse event reports collected by the FDA's Center for Veterinary Medicine. Each report includes the animal species, breed, drug or product involved, observed reactions, and outcome. Reports flagged as "serious" involve death, life-threatening conditions, or hospitalization. Use the filters to narrow results by species, outcome severity, or keyword. Note that a higher number of reports does not necessarily indicate a less safe product — widely prescribed drugs naturally accumulate more reports.
Pet Adverse Event Reports
Browse 1,493 FDA veterinary adverse event reports for Other.
| Date | Species | Breed | Drug | Reaction | Outcome |
|---|---|---|---|---|---|
| Jan 22, 1996 | Other | Unknown | Pentobarbital, Phenytoin | Lack of efficacy - NOS | Died |
| Jan 22, 1996 | Other | Unknown | Pentobarbital, Phenytoin | Lack of efficacy - NOS | Died |
| Jan 22, 1996 | Other | Unknown | Pentobarbital, Phenytoin | Lack of efficacy - NOS | Died |
| Jan 22, 1996 | Other | Unknown | Pentobarbital, Phenytoin | Lack of efficacy - NOS | Died |
| Jan 22, 1996 | Other | Unknown | Pentobarbital, Phenytoin | Lack of efficacy - NOS | Died |
| Jan 22, 1996 | Other | Unknown | Pentobarbital, Phenytoin | Lack of efficacy - NOS | Died |
| Jan 22, 1996 | Other | Unknown | Pentobarbital, Phenytoin | Lack of efficacy - NOS | Died |
| Dec 14, 1995 | Other | Unknown | Xylazine | INEFFECTIVE, SEDATION | — |
| Nov 27, 1995 | Other | Unknown | Ketamine Hydrochloride | Death | Died |
| Nov 1, 1995 | Other | Unknown | Ampicillin Trihydrate | Injection site pain | — |
| Oct 3, 1995 | Other | Unknown | Methylprednisolone Acetate | Uraemia; Hepatopathy; Hyperglycaemia; Death | Died |
| Aug 21, 1995 | Other | Unknown | Methoxyflurane | INEFFECTIVE, ANESTHESIA | — |
| Aug 8, 1995 | Other | Unknown | Ketamine Hydrochloride | INEFFECTIVE, ANESTHESIA | — |
| Jul 31, 1995 | Other | Unknown | Butorphanol Tartrate | Bradycardia; Cardiac arrest; Bradypnoea | — |
| Jul 20, 1995 | Other | Unknown | Isoflurane | INEFFECTIVE, ANESTHESIA | — |
| Jul 13, 1995 | Other | Unknown | Ketamine Hydrochloride | INEFFECTIVE, ANESTHESIA | — |
| Jul 13, 1995 | Other | Unknown | Ketamine Hydrochloride | Cardiac arrest; Death | Died |
| Jul 13, 1995 | Other | Unknown | Ketamine Hydrochloride | INEFFECTIVE, ANESTHESIA | — |
| Jul 13, 1995 | Other | Unknown | Ketamine Hydrochloride | Cyanosis | — |
| Jul 5, 1995 | Other | Unknown | Praziquantel | Injection site pain | — |
| Jun 23, 1995 | Other | Unknown | Pentobarbital, Phenytoin | Lack of efficacy - NOS | — |
| Jun 20, 1995 | Other | Unknown | Ivermectin | Paralysis | — |
| Jun 14, 1995 | Other | Unknown | Pentobarbital, Phenytoin | Lack of efficacy - NOS | — |
| May 30, 1995 | Other | Unknown | Pentobarbital, Phenytoin | Lack of efficacy - NOS | — |
| May 30, 1995 | Other | Unknown | Pentobarbital, Phenytoin | Lack of efficacy - NOS | — |
| Apr 12, 1995 | Other | Unknown | Pentobarbital, Phenytoin | Lack of efficacy - NOS | — |
| Mar 13, 1995 | Other | Unknown | Ketamine Hydrochloride | INEFFECTIVE, ANESTHESIA | — |
| Mar 3, 1995 | Other | Unknown | Ivermectin | Apnoea; Death; Collapse (see also 'Cardio-vascular' and 'Systemic disorders') | Died |
| Feb 14, 1995 | Other | Unknown | Ketamine Hydrochloride | INEFFECTIVE, ANESTHESIA; Death | Died |
| Feb 9, 1995 | Other | Unknown | Ampicillin Trihydrate | Injection site swelling | — |
| Feb 8, 1995 | Other | Unknown | Tiletamine, Zolazepam | No sign | — |
| Feb 8, 1995 | Other | Unknown | Tiletamine, Zolazepam | Prolonged anaesthesia | — |
| Feb 6, 1995 | Other | Unknown | Bacitracin, Neomycin, Polymyxin B | Corneal ulcer | — |
| Feb 6, 1995 | Other | Unknown | Bacitracin, Neomycin, Polymyxin B | Eye irritation | — |
| Jan 23, 1995 | Other | Unknown | Acepromazine Maleate | INEFFECTIVE, TRANQUILIZATION | — |
| Jan 18, 1995 | Other | Unknown | Ketamine Hydrochloride | Swelling NOS; Ulceration NOS; Death; INEFFECTIVE, ANESTHESIA | Died |
| Dec 19, 1994 | Other | Unknown | Ivermectin | Cardiac disorder NOS; Death | Died |
| Nov 23, 1994 | Other | Unknown | Pentobarbital, Phenytoin | Lack of efficacy - NOS | Died |
| Oct 26, 1994 | Other | Unknown | Famphur | Regurgitation | Died |
| Oct 19, 1994 | Other | Unknown | Amprolium | Death | Died |
| Sep 9, 1994 | Other | Unknown | Amoxicillin | Injection site pain | — |
| Aug 26, 1994 | Other | Unknown | Amoxicillin | Injection site pain | — |
| Aug 10, 1994 | Other | Unknown | Pentobarbital, Phenytoin | Lack of efficacy - NOS | Died |
| Jul 29, 1994 | Other | Unknown | Pentobarbital, Phenytoin | Lack of efficacy - NOS | Died |
| Jun 23, 1994 | Other | Unknown | Ketamine Hydrochloride | INEFFECTIVE, SEDATION | — |
| Jun 15, 1994 | Other | Unknown | Pentobarbital, Phenytoin | Lack of efficacy - NOS | Died |
| May 16, 1994 | Other | Unknown | Sulfadimethoxine | Death | Died |
| May 9, 1994 | Other | Unknown | Ivermectin | Ataxia; Recumbency; Death | Died |
| May 4, 1994 | Other | Unknown | Methoxyflurane | Lack of efficacy - NOS | — |
| Apr 29, 1994 | Other | Unknown | Dexamethasone Sodium Phosphate | Cardiac arrest; Apnoea; Collapse (see also 'Cardio-vascular' and 'Systemic di... | — |
Frequently Asked Questions
Contact your veterinarian immediately. If the reaction is severe — difficulty breathing, seizures, collapse, or severe swelling — seek emergency veterinary care right away. After your pet is stabilized, report the adverse event to the FDA through safetyreporting.hhs.gov or by calling 1-888-FDA-VETS (1-888-332-8387). Reporting helps the FDA identify safety issues that can lead to label changes or product recalls.
Dogs account for the majority of adverse event reports, followed by cats. This reflects both the larger pet population and wider range of medications for these species. Flea and tick products, pain medications (NSAIDs), and heartworm preventives are among the product categories with the highest report counts across all species.
Not necessarily. A drug used by millions of pets will have more reports in absolute numbers than a niche product, even if the actual rate of adverse events is lower. The FDA uses these reports as one of many tools to evaluate drug safety, looking for patterns and statistical signals rather than raw counts alone. Always consult your veterinarian before changing any medication.