Browse Pet Safety Reports

1,493 FDA adverse event reports for pets.

FDA Veterinary Adverse Event Database

Browse 1,493 adverse event reports collected by the FDA's Center for Veterinary Medicine. Each report includes the animal species, breed, drug or product involved, observed reactions, and outcome. Reports flagged as "serious" involve death, life-threatening conditions, or hospitalization. Use the filters to narrow results by species, outcome severity, or keyword. Note that a higher number of reports does not necessarily indicate a less safe product, widely prescribed drugs naturally accumulate more reports.

Pet Adverse Event Reports

Browse 1,493 FDA veterinary adverse event reports for Other.

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Date Species Breed Drug Reaction Outcome
Sep 15, 1999 Other Unknown Penicillin G Benzathine, Penicillin G... Injection site abscess; Anaphylaxis; Death Died
Sep 10, 1999 Other Unknown Hyaluronate Sodium Lameness; Joint effusion -
Sep 9, 1999 Other Unknown Carprofen No sign; Accidental exposure -
Sep 6, 1999 Other Unknown Carprofen Elevated liver enzymes; Diarrhoea; Vomiting -
Sep 1, 1999 Other Unknown Tiletamine, Zolazepam INEFFECTIVE, ANESTHESIA -
Aug 28, 1999 Other Unknown Albendazole Ataxia -
Aug 24, 1999 Other Unknown Amoxicillin Injection site pain; Vocalisation -
Aug 21, 1999 Other Unknown Selamectin Otitis externa; Shaking -
Aug 15, 1999 Other Unknown Tiletamine, Zolazepam INEFFECTIVE, ANESTHESIA -
Aug 15, 1999 Other Unknown Isoflurane INEFFECTIVE, ANESTHESIA -
Aug 15, 1999 Other Unknown Pyrantel Pamoate INEFFECTIVE, ASCARIDS NOS -
Aug 1, 1999 Other Unknown Isoflurane INEFFECTIVE, ANESTHESIA -
Aug 1, 1999 Other Unknown Pentobarbital, Phenytoin INEFFECTIVE, EUTHANASIA Died
Jul 31, 1999 Other Unknown Ketamine Hydrochloride INEFFECTIVE, SEDATION -
Jul 15, 1999 Other Unknown Tiletamine, Zolazepam No sign -
Jul 12, 1999 Other Unknown Ampicillin Trihydrate Suspension, Abnormal -
Jul 9, 1999 Other Unknown Carprofen No sign; Accidental exposure -
Jul 8, 1999 Other Unknown Albendazole Seal, Abnormal -
Jul 8, 1999 Other Unknown Albendazole Seal, Abnormal -
Jul 8, 1999 Other Unknown Albendazole Locking Mechanism Abnormal -
Jul 1, 1999 Other Unknown Ketamine Hydrochloride INEFFECTIVE, ANESTHESIA -
Jun 30, 1999 Other Unknown Estradiol, Trenbolone Acetate Product Defect, General; Underfilling, Package -
Jun 27, 1999 Other Unknown Medetomidine INEFFECTIVE, SEDATION -
Jun 24, 1999 Other Unknown Pentobarbital, Phenytoin INEFFECTIVE, EUTHANASIA Died
Jun 8, 1999 Other Unknown Isoflurane INEFFECTIVE, ANESTHESIA -
May 27, 1999 Other Unknown Orbifloxacin Lack of efficacy (bacteria) - NOS -
May 27, 1999 Other Unknown Orbifloxacin Lack of efficacy (bacteria) - NOS; Labelled drug-drug interaction medication ... -
May 15, 1999 Other Unknown Isoflurane Prolonged anaesthesia; Cardiac arrest; Apnoea; Death; Recovery prolonged Died
May 13, 1999 Other Unknown Epsiprantel Lack of efficacy (endoparasite) - tapeworm -
May 1, 1999 Other Unknown Acepromazine Maleate Recovery prolonged; Sedation prolonged -
Apr 23, 1999 Other Unknown Xylazine INEFFECTIVE, SEDATION -
Apr 19, 1999 Other Unknown Butorphanol Tartrate Fever -
Apr 15, 1999 Other Unknown Tiletamine, Zolazepam INEFFECTIVE, ANESTHESIA -
Apr 15, 1999 Other Unknown Pentobarbital INEFFECTIVE, EUTHANASIA Died
Apr 8, 1999 Other Unknown Xylazine INEFFECTIVE, SEDATION -
Apr 6, 1999 Other Unknown Ketamine Hydrochloride Underfilling, Vials -
Apr 1, 1999 Other Unknown Doramectin Lack of efficacy - NOS -
Mar 23, 1999 Other Unknown Ketamine Hydrochloride INEFFECTIVE, ANESTHESIA -
Mar 6, 1999 Other Unknown Monensin Ataxia; Staggering; Death; Weakness Died
Mar 3, 1999 Other Unknown Ketamine Hydrochloride Underfilling, Vials; Vials, Damaged -
Mar 1, 1999 Other Unknown Ketamine Hydrochloride INEFFECTIVE, SEDATION -
Feb 25, 1999 Other Unknown Florfenicol Anaphylaxis; Death Died
Feb 22, 1999 Other Unknown Tiletamine, Zolazepam Death Died
Feb 4, 1999 Other Unknown Amoxicillin, Clavulanate UNPALATABLE -
Feb 1, 1999 Other Unknown Isoflurane INEFFECTIVE, ANESTHESIA -
Feb 1, 1999 Other Unknown Fenbendazole INEFFECTIVE, STRONGYLES; Death Died
Jan 26, 1999 Other Unknown Medetomidine No sign -
Jan 26, 1999 Other Unknown Atipamezole No sign -
Jan 22, 1999 Other Unknown Tiletamine, Zolazepam INEFFECTIVE, ANESTHESIA -
Jan 1, 1999 Other Unknown Sulfadimethoxine Lack of efficacy (protozoa) - Coccidia -

Frequently Asked Questions

Contact your veterinarian immediately. If the reaction is severe, difficulty breathing, seizures, collapse, or severe swelling, seek emergency veterinary care right away. After your pet is stabilized, report the adverse event to the FDA through safetyreporting.hhs.gov or by calling 1-888-FDA-VETS (1-888-332-8387). Reporting helps the FDA identify safety issues that can lead to label changes or product recalls.

Dogs account for the majority of adverse event reports, followed by cats. This reflects both the larger pet population and wider range of medications for these species. Flea and tick products, pain medications (NSAIDs), and heartworm preventives are among the product categories with the highest report counts across all species.

Not necessarily. A drug used by millions of pets will have more reports in absolute numbers than a niche product, even if the actual rate of adverse events is lower. The FDA uses these reports as one of many tools to evaluate drug safety, looking for patterns and statistical signals rather than raw counts alone. Always consult your veterinarian before changing any medication.