Browse Pet Safety Reports
1,493 FDA adverse event reports for pets.
FDA Veterinary Adverse Event Database
Browse 1,493 adverse event reports collected by the FDA's Center for Veterinary Medicine. Each report includes the animal species, breed, drug or product involved, observed reactions, and outcome. Reports flagged as "serious" involve death, life-threatening conditions, or hospitalization. Use the filters to narrow results by species, outcome severity, or keyword. Note that a higher number of reports does not necessarily indicate a less safe product — widely prescribed drugs naturally accumulate more reports.
Pet Adverse Event Reports
Browse 1,493 FDA veterinary adverse event reports for Other.
| Date | Species | Breed | Drug | Reaction | Outcome |
|---|---|---|---|---|---|
| Sep 15, 1999 | Other | Unknown | Penicillin G Benzathine, Penicillin G... | Injection site abscess; Anaphylaxis; Death | Died |
| Sep 10, 1999 | Other | Unknown | Hyaluronate Sodium | Lameness; Joint effusion | — |
| Sep 9, 1999 | Other | Unknown | Carprofen | No sign; Accidental exposure | — |
| Sep 6, 1999 | Other | Unknown | Carprofen | Elevated liver enzymes; Diarrhoea; Vomiting | — |
| Sep 1, 1999 | Other | Unknown | Tiletamine, Zolazepam | INEFFECTIVE, ANESTHESIA | — |
| Aug 28, 1999 | Other | Unknown | Albendazole | Ataxia | — |
| Aug 24, 1999 | Other | Unknown | Amoxicillin | Injection site pain; Vocalisation | — |
| Aug 21, 1999 | Other | Unknown | Selamectin | Otitis externa; Shaking | — |
| Aug 15, 1999 | Other | Unknown | Tiletamine, Zolazepam | INEFFECTIVE, ANESTHESIA | — |
| Aug 15, 1999 | Other | Unknown | Isoflurane | INEFFECTIVE, ANESTHESIA | — |
| Aug 15, 1999 | Other | Unknown | Pyrantel Pamoate | INEFFECTIVE, ASCARIDS NOS | — |
| Aug 1, 1999 | Other | Unknown | Isoflurane | INEFFECTIVE, ANESTHESIA | — |
| Aug 1, 1999 | Other | Unknown | Pentobarbital, Phenytoin | INEFFECTIVE, EUTHANASIA | Died |
| Jul 31, 1999 | Other | Unknown | Ketamine Hydrochloride | INEFFECTIVE, SEDATION | — |
| Jul 15, 1999 | Other | Unknown | Tiletamine, Zolazepam | No sign | — |
| Jul 12, 1999 | Other | Unknown | Ampicillin Trihydrate | Suspension, Abnormal | — |
| Jul 9, 1999 | Other | Unknown | Carprofen | No sign; Accidental exposure | — |
| Jul 8, 1999 | Other | Unknown | Albendazole | Seal, Abnormal | — |
| Jul 8, 1999 | Other | Unknown | Albendazole | Seal, Abnormal | — |
| Jul 8, 1999 | Other | Unknown | Albendazole | Locking Mechanism Abnormal | — |
| Jul 1, 1999 | Other | Unknown | Ketamine Hydrochloride | INEFFECTIVE, ANESTHESIA | — |
| Jun 30, 1999 | Other | Unknown | Estradiol, Trenbolone Acetate | Product Defect, General; Underfilling, Package | — |
| Jun 27, 1999 | Other | Unknown | Medetomidine | INEFFECTIVE, SEDATION | — |
| Jun 24, 1999 | Other | Unknown | Pentobarbital, Phenytoin | INEFFECTIVE, EUTHANASIA | Died |
| Jun 8, 1999 | Other | Unknown | Isoflurane | INEFFECTIVE, ANESTHESIA | — |
| May 27, 1999 | Other | Unknown | Orbifloxacin | Lack of efficacy (bacteria) - NOS | — |
| May 27, 1999 | Other | Unknown | Orbifloxacin | Lack of efficacy (bacteria) - NOS; Labelled drug-drug interaction medication ... | — |
| May 15, 1999 | Other | Unknown | Isoflurane | Prolonged anaesthesia; Cardiac arrest; Apnoea; Death; Recovery prolonged | Died |
| May 13, 1999 | Other | Unknown | Epsiprantel | Lack of efficacy (endoparasite) - tapeworm | — |
| May 1, 1999 | Other | Unknown | Acepromazine Maleate | Recovery prolonged; Sedation prolonged | — |
| Apr 23, 1999 | Other | Unknown | Xylazine | INEFFECTIVE, SEDATION | — |
| Apr 19, 1999 | Other | Unknown | Butorphanol Tartrate | Fever | — |
| Apr 15, 1999 | Other | Unknown | Tiletamine, Zolazepam | INEFFECTIVE, ANESTHESIA | — |
| Apr 15, 1999 | Other | Unknown | Pentobarbital | INEFFECTIVE, EUTHANASIA | Died |
| Apr 8, 1999 | Other | Unknown | Xylazine | INEFFECTIVE, SEDATION | — |
| Apr 6, 1999 | Other | Unknown | Ketamine Hydrochloride | Underfilling, Vials | — |
| Apr 1, 1999 | Other | Unknown | Doramectin | Lack of efficacy - NOS | — |
| Mar 23, 1999 | Other | Unknown | Ketamine Hydrochloride | INEFFECTIVE, ANESTHESIA | — |
| Mar 6, 1999 | Other | Unknown | Monensin | Ataxia; Staggering; Death; Weakness | Died |
| Mar 3, 1999 | Other | Unknown | Ketamine Hydrochloride | Underfilling, Vials; Vials, Damaged | — |
| Mar 1, 1999 | Other | Unknown | Ketamine Hydrochloride | INEFFECTIVE, SEDATION | — |
| Feb 25, 1999 | Other | Unknown | Florfenicol | Anaphylaxis; Death | Died |
| Feb 22, 1999 | Other | Unknown | Tiletamine, Zolazepam | Death | Died |
| Feb 4, 1999 | Other | Unknown | Amoxicillin, Clavulanate | UNPALATABLE | — |
| Feb 1, 1999 | Other | Unknown | Isoflurane | INEFFECTIVE, ANESTHESIA | — |
| Feb 1, 1999 | Other | Unknown | Fenbendazole | INEFFECTIVE, STRONGYLES; Death | Died |
| Jan 26, 1999 | Other | Unknown | Medetomidine | No sign | — |
| Jan 26, 1999 | Other | Unknown | Atipamezole | No sign | — |
| Jan 22, 1999 | Other | Unknown | Tiletamine, Zolazepam | INEFFECTIVE, ANESTHESIA | — |
| Jan 1, 1999 | Other | Unknown | Sulfadimethoxine | Lack of efficacy (protozoa) - Coccidia | — |
Frequently Asked Questions
Contact your veterinarian immediately. If the reaction is severe — difficulty breathing, seizures, collapse, or severe swelling — seek emergency veterinary care right away. After your pet is stabilized, report the adverse event to the FDA through safetyreporting.hhs.gov or by calling 1-888-FDA-VETS (1-888-332-8387). Reporting helps the FDA identify safety issues that can lead to label changes or product recalls.
Dogs account for the majority of adverse event reports, followed by cats. This reflects both the larger pet population and wider range of medications for these species. Flea and tick products, pain medications (NSAIDs), and heartworm preventives are among the product categories with the highest report counts across all species.
Not necessarily. A drug used by millions of pets will have more reports in absolute numbers than a niche product, even if the actual rate of adverse events is lower. The FDA uses these reports as one of many tools to evaluate drug safety, looking for patterns and statistical signals rather than raw counts alone. Always consult your veterinarian before changing any medication.