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Top Toxic Chemicals Released

Most released chemicals from 21,482 facilities reporting to the EPA Toxics Release Inventory, totaling 0 pounds of chemical releases.

The EPA's Toxics Release Inventory (TRI) requires industrial facilities to report annual releases of listed toxic chemicals to air, water, land, and underground injection wells. Over 650 individual chemicals and chemical categories are covered by the TRI program. The chemicals listed here represent those with the highest total reported release volumes across all facilities and years in the database. Release volume alone does not indicate health risk, the toxicity, persistence, and proximity to populated areas are all relevant to assessing potential harm.

Top Chemicals by Release Volume

All TRI-listed chemicals ranked by total pounds released.

# Chemical Total Released (lbs) Records
1 Toluene diisocyanate (mixed isomers) 0 133
2 Xylene (mixed isomers) 0 1,980
3 Silver 0 67
4 Toluene-2,6-diisocyanate 0 34
5 Toluene-2,4-diisocyanate 0 60
6 Selenium compounds 0 97
7 Hydrogen fluoride 0 595
8 Sulfuric acid (acid aerosols including mists, vapors, gas, fog, and other airborne forms of any particle size) 0 528
9 Cobalt compounds 0 333
10 1-Bromopropane 0 50
11 Manganese compounds 0 1,516
12 1,2-Butylene oxide 0 13
13 Formic acid 0 341
14 Ammonia 0 2,142
15 Nitrilotriacetic acid 0 8
16 Nitromethane 0 6
17 Styrene 0 1,093
18 Dichloromethane 0 208
19 Ethyl acrylate 0 82
20 Toluene 0 2,143
21 Methyl methacrylate 0 325
22 1,2,4-Trimethylbenzene 0 1,187
23 Benzene 0 1,166
24 Cumene 0 566
25 Ethylbenzene 0 1,451
26 Phosphoric acid, γ-ω-perfluoro-C8-16-alkyl esters, compds. with diethanolamine 0 1
27 Sodium nitrite 0 354
28 Formaldehyde 0 703
29 Certain glycol ethers 0 1,401
30 Nitric acid 0 1,618
31 Copper compounds 0 1,452
32 Zinc compounds 0 2,820
33 Diisocyanates 0 1,353
34 Chlorine 0 517
35 Arsenic compounds 0 219
36 Chromium compounds (except for chromite ore mined in the Transvaal Region) 0 1,112
37 Lead 0 4,024
38 Nickel 0 2,525
39 Chromium 0 2,486
40 Methanol 0 2,197
41 Copper 0 2,348
42 Lead compounds 0 3,453
43 Naphthalene 0 1,227
44 4,4'-Methylenebis(2-chloroaniline) 0 24
45 Ethylene glycol 0 1,439
46 Mercury 0 330
47 Nonylphenol Ethoxylates 0 301
48 Manganese 0 2,284
49 Diazinon 0 11
50 Permethrin 0 17

CARC = classified as a known or suspected carcinogen.

Top Carcinogens Released

Known or suspected carcinogens with the highest total TRI release volumes.

# Chemical Total Released (lbs)

Carcinogen classification is based on the TRI reporting form field as designated by EPA, IARC, or NTP.

Understanding TRI Chemical Data

What TRI Measures

The Toxics Release Inventory captures releases and transfers of toxic chemicals from manufacturing, mining, electric utilities, and other covered industries. Releases are reported by pathway: stack air emissions, fugitive air emissions (leaks and evaporation), surface water discharges, underground injection, and land disposal including landfills. Facilities must also report off-site transfers of waste for treatment and disposal. The TRI does not cover all industries or all chemicals, it represents a significant but incomplete picture of industrial chemical activity in the United States.

High Volume vs. High Risk

Some of the highest-volume TRI chemicals, like nitrate compounds, hydrochloric acid, and ammonia, are released in very large quantities but may disperse rapidly or have limited persistent health effects compared to lower-volume releases of highly toxic compounds. Carcinogen releases are of particular concern because they represent exposures that can contribute to cancer risk over long time periods and at very low concentrations. When evaluating chemical risk in your area, the EPA's TRI Explorer and the agency's Risk-Screening Environmental Indicators (RSEI) model provide more nuanced risk-adjusted analysis than raw release weights alone.

Explore Environmental Hazards Data

Browse Superfund sites by state, or search TRI releases by facility or chemical.

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